The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Brown Adipose Tissue Clinical Trial

Official title:

The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02038595
• Other study ID #: 1008007284
• Status: Completed
• Phase: Early Phase 1
• Start date: September 2012
• Est. completion date: December 2013

Study information

• Verified date: July 2015
• Source: Yale University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study seeks to assess a novel imaging technique to image brown adipose tissue utilizing the norepinephrine transporter.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: December 2013
• Est. primary completion date: December 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• age 18-30 yrs

• BMI < 24 kg/m2

• Caucasian

Exclusion Criteria:

• Current neuro-psychiatric illness

• substance abuse

• medical or neurological illnesses likely to affect physiology or anatomy, i.e., uncontrolled hypertension, cardiovascular disorders

• current pregnancy

• current breast feeding

• suicidal ideation or behavior

• use of medications which potentially affect NET binding within 2 weeks of the PET scans.

Related Conditions & MeSH terms

• Brown Adipose Tissue

Intervention

Radiation:
• PET imaging

Locations

Country	Name	City	State
United States	Yale University	New Haven	Connecticut

Sponsors (2)

Lead Sponsor	Collaborator
Yale University	NYU Langone Health

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	detection of brown adipose tissue based on PET imaging		1 year