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NCT05956301 Clinical Trial

Effects of Different Ventilatory Strategy During Bronchoscopy

Bronchoscopy Clinical Trial

Official title:
Effects of Different Ventilatory Strategy During Bronchoscopy

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05956301
Other study ID # 20230618
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date July 20, 2023
Est. completion date June 30, 2025

Study information
Verified date July 2023
Source The First Affiliated Hospital of Guangzhou Medical University
Contact Liya Lu
Phone +86-020-83062885
Email 2412183636@qq.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures. Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 150
Est. completion date June 30, 2025
Est. primary completion date June 30, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years to 85 Years
Eligibility Inclusion Criteria: - need for bronchial endoscopy Exclusion Criteria: - life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Conventional Oxygen Therapy
Conventional Oxygen Therapy will be administered through Nasal catheter
• High-flow nasal oxygen
High Flow Nasal Cannula will be administered
• Supraglottic jet oxygenation and ventilation
Nasal jet tube will be administered

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
The First Affiliated Hospital of Guangzhou Medical University

Outcome
Type Measure Description Time frame Safety issue
Primary Compare the intraoperative oxygenation. The study will monitor the SpO2, heart rate(HR) and mean arterial pressure (MAP) during the procedure. During bronchoscopy, an average of 0.5 hour.
Secondary Arterial blood gases Arterial blood gas analysis will be monitored at end of of procedure. At end of of bronchoscopy,an average of 0.5 hour after bronchoscope insertion.
Secondary Assess the regional ventilation distribution by Electrical impedance tomography . Measurements will be done after bronchoscope insertion and at the end of the procedure. During bronchoscopy, an average of 0.5 hour.
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