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Clinical Trial Summary

This study is an open-label, phase 1, sequential dose escalation trial seeking to establish preliminary tolerability, efficacy, and pharmacokinetic data for up to 4 different doses of inhaled tobramycin administered to very preterm infants with BPD who are receiving invasive mechanical ventilation and have a pathogenic Gram-negative organism detected by tracheal aspirate culture.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04560179
Study type Interventional
Source Children's Hospital of Philadelphia
Contact Erik A Jensen, MD MSCE
Phone 2676482720
Email jensene@chop.edu
Status Recruiting
Phase Phase 1
Start date March 22, 2022
Completion date March 1, 2025

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