Bronchopulmonary Dysplasia Clinical Trial
Official title:
Forced Oscillometry in Infants With Bronchopulmonary Dysplasia
The purpose of this study is to use forced oscillometry technique (FOT) to measure pulmonary mechanics and function in in term infants and premature infants with bronchopulmonary dysplasia (BPD)
Status | Recruiting |
Enrollment | 70 |
Est. completion date | December 2024 |
Est. primary completion date | December 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: Preterm Cohort: - Premature infants with BPD who are in room air based on the (per NICHD definition) - Premature infants with BPD who are receiving low flow O2 support and able to maintain normal spO2 in Room air for brief period ( up to 3 minutes) Term Cohort without pulmonary disease - Infants >36 weeks gestational age without pulmonary disease - Infants < 4 weeks of age Exclusion Criteria: - Infants with BPD requiring invasive or non-invasive positive pressure ventilation - Infants with BPD who have associated genetic diagnosis or major congenital anomalies. |
Country | Name | City | State |
---|---|---|---|
United States | Children's Mercy Hospital | Kansas City | Missouri |
Lead Sponsor | Collaborator |
---|---|
Winston Manimtim |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Forced oscillation technique measurements | Baseline FOT measurements in premature infants with BPD and term infants without pulmonary disease. | FOT measurement prior to bronchodilator therapy | |
Primary | Post-bronchodilator forced oscillation technique measurements (in subjects already receiving this therapy) | FOT measurements in premature infants with BPD following bronchodilator therapy. | FOT measurement 30 to 60minutes following bronchodilator therapy |
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