Bronchopulmonary Dysplasia Clinical Trial
— AeroBPDOfficial title:
Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD
Investigators want to learn the role of indoor environmental exposures on respiratory symptoms, and, separately, on lung function deficits in school-aged children with bronchopulmonary dysplasia (BPD).
Status | Recruiting |
Enrollment | 240 |
Est. completion date | July 31, 2025 |
Est. primary completion date | July 31, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 6 Years to 12 Years |
Eligibility | Inclusion Criteria: - children 6-12 yrs old - born <32 wks gestational age - diagnosis of BPD or > 28 days of oxygen or respiratory support Exclusion Criteria: - major airway or chest surgery - physical or mental impairment that will prevent from doing spirometry - plans to move out of state within the next 9 months |
Country | Name | City | State |
---|---|---|---|
United States | Boston Childrens Hospital | Boston | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Boston Children's Hospital | National Institute of Environmental Health Sciences (NIEHS) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Respiratory Morbidity | maximum symptom days in the prior 2 weeks assessed at completion of home sampling visits ( Units: days scale: 0-14 days with symptoms, higher is worse | 2 weeks | |
Primary | Lung Function | Spirometry (FEV1 percent predicted) Units: percent Scale: continuous integers, higher is better | 1 yr | |
Secondary | Lung function | Oscillometry (R5-20) | 1 year | |
Secondary | Lung function | Oscillometry (AX) units: cmH20 scale 0 - infinity, lower is better | 1 year | |
Secondary | Lung function | Oscillometry R5 units: cmH20 scale 0 - infinity, lower is better | 1 year | |
Secondary | Lung function | Oscillometry R5-20 units: cmH20 scale 0 - infinity, lower is better | 1 year | |
Secondary | Lung function | Oscillometry X5 units: cmH20 scale 0 - infinity, lower is better | 1 year | |
Secondary | Lung function | Oscillometry Fres units: Hz scale 0 - infinity, lower is better | 1 year | |
Secondary | Lung Function | FEV1/FVC units: percent scale: continuous integer, higher is better | 1 year | |
Secondary | Lung Function | FVC percent predicted units: percent scale: continuous integer, higher is better | 1 year | |
Secondary | Lung Function | FEF25-75 percent predicted units: percent scale: continuous integer, higher is better | 1 year |
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