Clinical Trials Logo

Clinical Trial Summary

The study will conduct with 4 comparative groups orally treated with YHD001 dose level 1(t.i.d.), YHD001 dose level 2(t.i.d.), pelargonium sidoides extract 9mL(t.i.d.) or Placebo for 7 days.

The treatments will be assigned randomly to patients (n=116) with acute or chronic bronchitis.


Clinical Trial Description

The outcome measures is to evaluate the overall change from baseline to the end of treatment in scores relating to the severity of four symptom of bronchitis: cough, sputum, QOL of daily life, QOL of falling asleep at night. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01420445
Study type Interventional
Source Yuhan Corporation
Contact
Status Completed
Phase Phase 2
Start date September 2011
Completion date May 2012

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05533931 - Resistive Breathing Versus Inspiratory Hold Technique in Patients With Chronic Bronchitis N/A
Completed NCT01071161 - The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough Phase 3
Terminated NCT00524095 - Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis Phase 2
Completed NCT00903955 - Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung Disease N/A
Completed NCT00129883 - Adherence to Guidelines for Antibiotic Use in Respiratory Infections at Hospitals N/A
Recruiting NCT05075057 - Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Patients Aged ≥60 Years With Chronic Bronchitis and COPD Phase 4
Recruiting NCT05075083 - Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPD Phase 4
Terminated NCT02838108 - The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort
Completed NCT02128529 - Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD) N/A
Completed NCT00298389 - Macrophage Phagocytosis in COPD
Withdrawn NCT00298402 - Macrophages in Smokers' Lung N/A
Terminated NCT00132951 - KEYS: Study Comparing Clinical Health Outcomes of Telithromycin Versus Azithromycin in Outpatients With Community-acquired Lower Respiratory Tract Infections Phase 4
Active, not recruiting NCT01969344 - Study of COPD Subgroups and Biomarkers
Completed NCT00680056 - Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients Phase 4
Completed NCT00106080 - Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD) N/A
Completed NCT00042718 - A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis. Phase 3
Completed NCT02099799 - The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD N/A
Completed NCT00342030 - Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans N/A
Withdrawn NCT02341183 - Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB Subjects N/A
Completed NCT00876577 - VICTOR - Avelox® Intravenous (i.v.) in Acute Exacerbations of Chronic Bronchitis N/A