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Clinical Trial Summary

To measure the speed of bacterial eradication from the respiratory tract after administration of azithromycin or telithromycin.


Clinical Trial Description

To Evaluate the relationship between rate of S. pneumoniae killing in sputum, PK/PD, and clinical response of oral telithromycin and azithromycin in patients with AECB or CAP and to determine if there is a difference in the rates of infection site bacterial killing (as described above) between these 3 antibiotics against penicillin- and erythromycin-resistant S.pneumoniae ;


Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00245453
Study type Interventional
Source CPL Associates
Contact
Status Withdrawn
Phase Phase 4
Start date October 2005
Completion date July 2006

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