Clinical Trials Logo
  1. Home
  2. Bronchiolitis
  3. NCT04814641
  4. Details
NCT04814641 Clinical Trial

Hypophosphatemia and Bronchiolitis

Bronchiolitis Clinical Trial

Official title:
Hypophosphatemia In Infants With Severe Bronchiolitis: Prevalence And Risk Factors

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04814641
Other study ID # A289
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date March 21, 2021
Est. completion date June 2021

Study information
Verified date March 2021
Source Hospices Civils de Lyon
Contact Florent Baudin, Dr
Phone 4 72 12 97 35
Email florent.baudin@chu-lyon.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the duration of mechanical ventilation and the length of stay. Our hypothesis is that hypophosphatemia is common in bronchiolitis and could be a marker of severity.

Recruitment information / eligibility
Status Recruiting
Enrollment 400
Est. completion date June 2021
Est. primary completion date May 2021
Accepts healthy volunteers No
Gender All
Age group N/A to 3 Months
Eligibility Inclusion Criteria: - Age > 7 days and < 3 months of life - Admission to the pediatric intensive care unit from 01/11/2016 to 31/03/2020 - With a diagnosis of moderate to severe bronchiolitis according to HAS 2019 criteria Exclusion Criteria: - Renal Failure and tubulopathy - Previous disorder of phospho-calcium balance - Malignant pathology - Lenght of stay less than 24 hours - History of cardiac, aortic or hepatic surgery

Study Design

Related Conditions & MeSH terms

Intervention

Biological:
• hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit
Serum phosphorus level < 1.55 mmol/L at any time between admission and the 5th day.

Locations
Country Name City State
France Hopital Femme Mere Enfant - Groupement Hospitalier Est Bron

Sponsors (1)
Lead Sponsor Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary hypophosphatemia occurrence in severe bronchiolitis in infants admitted in a pediatric intensive care unit A serum phosphorus level< 1.55mmol/L defines the hypophosphatemia. At any time in the first 5th days after Pediatric intensive care admission
See also
  Status Clinical Trial Phase
Recruiting NCT04989114 - Nasal Bubble Continuous Positive Airway Pressure in Reducing Respiratory Distress in Children With Bronchiolitis N/A
Recruiting NCT06016244 - Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial N/A
Not yet recruiting NCT05902702 - Isotonic Saline for Children With Bronchiolitis N/A
Recruiting NCT02366715 - Treatment Of Bronchiolitis With Heated Humidified High Flow Nasal Cannula - Prospective And Retrospective Research Phase 3
Terminated NCT02219334 - Comparing Nasal Suction Devices in Children With Bronchiolitis: A Pilot Study N/A
Recruiting NCT01944995 - Work of Breathing in Nasal CPAP Versus High Flow Nasal Prong in Infants With Severe Acute Bronchiolitis N/A
Terminated NCT02834819 - Nebulized 3% Hypertonic Saline vs. Standard of Care in Patients With Bronchiolitis N/A
Terminated NCT01757496 - Cough Assist in Bronchiolitis N/A
Not yet recruiting NCT01414322 - Documentation of Continuous Wheeze and Cough Dynamics in Pediatric ER SOB Patients N/A
Completed NCT00369759 - An Epidemiological Study to Evaluate the RSV-Associated Lower Respiratory Track in Infections in Infants N/A
Completed NCT00347880 - Atrial and Brain Natriuretic Peptides in Bronchiolitis Phase 1
Recruiting NCT05548036 - A Feasibility RCT of Aerobika Verses ACBT in People With COPD N/A
Active, not recruiting NCT04302207 - The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study N/A
Completed NCT02858531 - Predictive Tracking of Patient Flow in the Emergency Services During the Virus Winter Epidemics
Withdrawn NCT05994183 - The Bronchiolitis in Hospitalized Infants Study Early Phase 1
Terminated NCT03614507 - Automation Oxygen Flow Titration in Spontaneously Breathing Infants N/A
Completed NCT02856165 - High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis N/A
Recruiting NCT05909566 - Respiratory Support and Treatment for Efficient and Cost-Effective Care N/A
Recruiting NCT04437641 - Impact of Pediatrician Intervention on the Smoking Habits of Parents of Sick Children
Not yet recruiting NCT06083077 - Chest and Abdominal Wall Strapping in Infant With Bronchiolitis N/A