Immune Mechanisms of Rejection in Human Lung Allografts

Status Completed

Clinical Trial Summary

The investigators have obtained compelling evidence that the development of anti-human leukocyte antigen (anti-HLA) antibodies against mismatched donor antigens significantly correlates with the development of bronchiolitis obliterans (BOS). Further, these anti-HLA antibodies are developed at least 15 months prior to any clinical evidence of BOS. This lag period between the development of anti-HLA antibodies and the onset of BOS gives us an opportunity to intervene to delay and/or prevent the development of BOS.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00861900
Study type	Observational
Source	Washington University School of Medicine
Contact
Status	Completed
Phase
Start date	January 1998
Completion date	July 2017

View Details

See also
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