Artificial Intelligence in Computed Tomography for Quantifying Lung Changes of Bronchiectasis Patients

Bronchiectasis Clinical Trial

Official title:

Artificial Intelligence Based on Machine Learning in Computed Tomography for Quantifying Lung Changes of Bronchiectasis Patients

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05751538
• Other study ID #: AI-BE
• Status: Not yet recruiting
• Start date: March 1, 2023
• Est. completion date: December 30, 2023

Study information

• Verified date: November 2022
• Source: Ruijin Hospital
• Contact: Jieming Qu
• Phone: 86-021-64370045
• Email: jmqu0906[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Bronchiectasis is a chronic respiratory disease characterized by permanent bronchiectasis.The incidence and prevalence of bronchiectasis have assumed continuously grows in global. Chest computed tomography (CT) remains the imaging standard for demonstrating cystic fibrosis (CF) airway structural disease in vivo. However, visual scoring systems as an outcome measure are time consuming, require training and lack high reproducibility. Our objective was to validate a fully automated artificial intelligence (AI)-driven scoring system of CF lung disease severity.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 730
• Est. completion date: December 30, 2023
• Est. primary completion date: June 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients diagnosed with bronchiectasis (according to the Chinese consensus, patient's previous chest CT examination must show bronchiectasis)

Exclusion Criteria:

• Patients with CT data and medical records missing

Related Conditions & MeSH terms

• Bronchiectasis

Intervention

Other:
• No intervention
No intervention

Locations

Country	Name	City	State
China	Ruijin Hospital, Medical School of Shanghai Jiaotong University	Shanghai	Shanghai

Sponsors (1)

Lead Sponsor	Collaborator
Ruijin Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlations of the artificial intelligence-driven scores with manual scores	Correlations and comparisons of the artificial intelligence-driven scores with manual scores by thoracic radiologists on CT scans of bronchiectasis patients.	From date of inclusion until the date of final quantification, assessed up to 12 months
Secondary	Correlation of the artificial intelligence-driven scores with pulmonary function test	Correlation of quantitative measurement with pulmonary function	From date of inclusion until the date of final quantification, assessed up to 12 months