Mucus Solids Concentration in Patients With Bronchiectasis

Status Recruiting

Clinical Trial Summary

There is a need for biomarkers that can rapidly and sensitively detect therapeutic benefits of therapies designed to "rehydrate" airways and monitor disease severity and progression. In this study the investigators will evaluate the stability of mucus concentration in patients with bronquiectasis (CF and NCBF) and its ability to respond to acute exacerbations in order to assess whether it can be a good candidate for biomarker.

Clinical Trial Description

Prospective cross-sectional study of repeated measurements. The recruitment will be performed in 3 different cities of Spain: Zaragoza, Barcelona and Murcia. Subjects will be asked to repeatedly collect spontaneous and induced sputum samples in both stable and exacerbated conditions. All samples will be collected autonomously by patients in their homes after they have been instructed and supervised. Hypertonic saline nebulization will be used for sputum induction. ;

Study Design

Related Conditions & MeSH terms

Bronchiectasis

Clinical Trial Details

NCT number	NCT04310618
Study type	Observational
Source	Universidad San Jorge
Contact	Marta San Miguel Pagola, PhD
Phone	34617086431
Email	msanmiguel@usj.es
Status	Recruiting
Phase
Start date	December 21, 2020
Completion date	August 2023

View Details

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