Bronchiectasis Clinical Trial
Official title:
Effects of High Intensity Inspiratory Muscle Training on Exercise Capacity in Patients With Bronchiectasis
Reduced exercise tolerance is commonly reported in patients with bronchiectasis. The purpose of this study is to evaluate the effects of high-intensity inspiratory muscle training (High-IMT) and sham High-IMT (control) on exercise capacity, respiratory muscle function (strength and endurance) and health related quality of life in patients with bronchiectasis.
Bronchiectasis often demonstrates decreased exercise tolerance, marked dyspnea and fatigue.
The causes are multifactorial and include altered pulmonary mechanics, inefficient gas
exchange, decreased muscle mass, and psychological status, which all lead to a progressive
detraining effect. Essentially both the pathology and the functional manifestations of
bronchiectasis increase the demand for inspiratory muscle work and that contribute to dyspnea
and exercise limitation.
In recent studies reduced strength of respiratory muscles are investigated in bronchiectasis
and can be contribute the exercise limitation. Additionally IMT has shown to improve
respiratory muscle function, exercise tolerance and dyspnea in patients with bronchiectasis.
Despite this, the number of studies are inadequate and so the optimal training protocol
remains still to be defined. In this study the researchers want to investigate the effects of
high-intensity inspiratory muscle training in functional results in patients with
bronchiectasis.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05034900 -
Does Addition of Oscillatory Positive Expiratory Pressure (OPEP) Device to a Chest Physiotherapy Program Provide Further Health Benefits in Children With Bronchiectasis?
|
N/A | |
| Recruiting |
NCT04101448 -
Prevalence of Bronchiectasis in COPD Patients
|
||
| Withdrawn |
NCT03376204 -
Pain Mechanisms in Patients With Bronchiectasis
|
||
| Completed |
NCT02550821 -
Comparison of Physical Activity Level Between Patients With Bronchiectasis and Healthy Subjects
|
||
| Completed |
NCT02048397 -
Pulmonary Rehabilitation Program (PRP) Versus PRP Plus Nutritional Supplementation in Patients With Bronchiectasis
|
N/A | |
| Completed |
NCT01615484 -
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
|
N/A | |
| Completed |
NCT02282202 -
Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD
|
N/A | |
| Recruiting |
NCT01761214 -
Bacteriology and Inflammation in Bronchiectasis
|
N/A | |
| Recruiting |
NCT02527486 -
Seoul National University Airway Registry
|
N/A | |
| Completed |
NCT01578681 -
ELTGOL and Bronchiectasis. Respiratory Therapy
|
N/A | |
| Completed |
NCT01854788 -
3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis
|
N/A | |
| Completed |
NCT00769119 -
A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis
|
Phase 2 | |
| Terminated |
NCT00524095 -
Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis
|
Phase 2 | |
| Completed |
NCT01117493 -
Expert Patient Self-management Programme Versus Usual Care in Bronchiectasis
|
N/A | |
| Recruiting |
NCT00129350 -
Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation
|
Phase 1 | |
| Completed |
NCT00656721 -
Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients
|
N/A | |
| Completed |
NCT04081740 -
Biological Determinants of Sputum Rheology in Chronic Airway Diseases
|
||
| Enrolling by invitation |
NCT02546297 -
Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With Bronchiectasis
|
Phase 4 | |
| Completed |
NCT03628456 -
Effect of HFCWO Vests on Spirometry Measurements
|
N/A | |
| Completed |
NCT03750734 -
Target Validation and Discovery in Idiopathic Bronchiectasis
|