Hypertonic Saline (6%) Versus Isotonic Saline (0.9%) in Bronchiectasis

Status Recruiting

Clinical Trial Summary

The investigators hypothesise that nebulised hypertonic saline (6%) will increase the volume of sputum expectorated over a 24 hour period compared to nebulised isotonic saline (0.9%) in patients with mild to severe stable bronchiectasis.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Bronchiectasis

Clinical Trial Details

NCT number	NCT01112410
Study type	Interventional
Source	Belfast Health and Social Care Trust
Contact
Status	Recruiting
Phase	Phase 2
Start date	January 2010
Completion date	August 2010

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05034900` - Does Addition of Oscillatory Positive Expiratory Pressure (OPEP) Device to a Chest Physiotherapy Program Provide Further Health Benefits in Children With Bronchiectasis?	N/A
Recruiting	`NCT04101448` - Prevalence of Bronchiectasis in COPD Patients
Withdrawn	`NCT03376204` - Pain Mechanisms in Patients With Bronchiectasis
Completed	`NCT02550821` - Comparison of Physical Activity Level Between Patients With Bronchiectasis and Healthy Subjects
Completed	`NCT02656992` - Effects of High Intensity Inspiratory Muscle Training on Exercise Capacity in Patients With Bronchiectasis	N/A
Completed	`NCT02282202` - Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD	N/A
Completed	`NCT01615484` - Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability	N/A
Completed	`NCT02048397` - Pulmonary Rehabilitation Program (PRP) Versus PRP Plus Nutritional Supplementation in Patients With Bronchiectasis	N/A
Recruiting	`NCT01761214` - Bacteriology and Inflammation in Bronchiectasis	N/A
Recruiting	`NCT02527486` - Seoul National University Airway Registry	N/A
Completed	`NCT01578681` - ELTGOL and Bronchiectasis. Respiratory Therapy	N/A
Completed	`NCT01854788` - 3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis	N/A
Completed	`NCT00769119` - A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis	Phase 2
Completed	`NCT01117493` - Expert Patient Self-management Programme Versus Usual Care in Bronchiectasis	N/A
Terminated	`NCT00524095` - Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis	Phase 2
Recruiting	`NCT00129350` - Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation	Phase 1
Completed	`NCT00656721` - Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients	N/A
Completed	`NCT04081740` - Biological Determinants of Sputum Rheology in Chronic Airway Diseases
Enrolling by invitation	`NCT02546297` - Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With Bronchiectasis	Phase 4
Completed	`NCT03628456` - Effect of HFCWO Vests on Spirometry Measurements	N/A