Breathing Clinical Trial
Official title:
Diagnostic Accuracy of the Central Venous Pressure (CVP) Variation to Predict Fluid Responsiveness in Spontaneously Breathing Patients
Volume expansion (VE) is often administered in intensive care (ICU)-patient to improve
arterial oxygen delivery. Such effect is secondary to an increase in stroke volume and
cardiac output. However, cardiac output increase in response to VE (fluid responsiveness)
only occurs when the heart is preload-dependant. Increasing evidence of the deleterious
effects of inappropriate fluid administration encourages the development of variables
predicting fluid responsiveness, but few have been validated in spontaneously breathing
patients.
Central venous pressure (CVP) variation in spontaneously patients during standardized or
unstandardized inspiratory maneuver may represent an easy tool to predict fluid
responsiveness. The hypothesise is that inspiratory maneuver may increase CVP variation in
fluid responsiveness patient whereas no or few variation may reflect fluid unresponsiveness.
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