Fluid Infusion During Breast Surgery

Status Not yet recruiting

Clinical Trial Summary

The investigators want to investigate the effects of two different kinds of fluid infusions given during varicose vein surgery. Both types of fluid are regularly given during surgery, and the investigators want to compare their respective effects on balance, nausea/vomiting and orthostatic function after surgery.

The investigators' hypothesis is that using a colloid solution will improve orthostatic function, balance, nausea/vomiting and reduce hospital stay.

Clinical Trial Description

The optimal amount and type of fluid given during surgery has not been defined. It has been agreed that hypovolemia must be avoided, but at the same time it has been agreed that fluid excess is harmful for organ function.When distributing fluids it is usually either crystalloids og colloids which are given. The effects of the two types of fluid have not been compared. Our hypothesis is that using a colloid (HES 130/0,4) will improve orthostatic function, nausea/vomiting and shorten hospital stay, compared to using a crystalloid (Lactated Ringer's solution).The amount of fluid the patient receives, will be individually tailored by monitoring SV using esophageal Doppler technique during surgery. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Breast Surgery

Clinical Trial Details

NCT number	NCT00431743
Study type	Interventional
Source	Rigshospitalet, Denmark
Contact	Morten Bundgaard-Nielsen, M.D.
Phone	0045 35452674
Email	morten.bundgaard-nielsen@rh.hosp.dk
Status	Not yet recruiting
Phase	Phase 4
Start date	April 2009
Completion date	September 2009

View Details

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