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Long-term Oncologic Outcome of Breast-conserving Surgery in Breast Cancer Patients With BRCA1/2 Mutations

Breast-conserving Surgery Clinical Trial

Official title:
Ong-term Oncologic Outcome of Breast-conserving Surgery in Breast Cancer Patients With BRCA1/2 Mutations

Clinical Trial Summary

The investigators matched BCS and mastectomy group using propensity scores and analyzed the recurrence and survival among the evenly matched patients in breast cancer patients with BRCA 1/2 mutations.

Clinical Trial Description

The purpose of study is to assess the oncologic safety of BCS in patients carrying BRCA1/2 mutations by comparing long-term outcomes with mastectomy. The investigators matched BCS and mastectomy group using propensity scores and analyzed the recurrence and survival among the evenly matched patients. By providing insights into the feasibility of BCS for patients with BRCA1/2 mutations, the investigators aim to present evidence to aid in surgical decision-making for the care of these patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06429644
Study type Observational
Source Hanyang University Seoul Hospital
Contact
Status Completed
Phase
Start date July 7, 2022
Completion date April 8, 2024
View Details
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