Brain Tumor Clinical Trial
Official title:
Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy
Verified date | January 2023 |
Source | Trakya University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The aim of this study is to determine the effects of the level of metabolites used in routine on mortality and morbidity in patients who will undergo intracranial surgery with craniotomy.
Status | Completed |
Enrollment | 100 |
Est. completion date | July 10, 2022 |
Est. primary completion date | December 10, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: 1. Having an intracranial mass operation with craniotomy 2. No history of congestive heart failure 3. No kidney and liver dysfunction 4. Not pregnant 5. Not taking inotropic drugs during the operation 6. Receiving less than four red blood product replacements during the operation Exclusion Criteria: 1. Patients with a history of congestive heart failure 2. Patients with kidney and liver dysfunction 3. Patients who need an inotropic agent to adjust blood pressure during the operation 4. Patients who have undergone four or more red blood product transfusions during the operation 5. Pregnant patients |
Country | Name | City | State |
---|---|---|---|
Turkey | Trakya University | Edirne | Centrum |
Lead Sponsor | Collaborator |
---|---|
Trakya University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | lactate level | Lactate, a byproduct of glycolysis, is an indicator of weak tissue perfusion and a useful biomarker with prognostic value in various diseases. Lactate value is calculated by blood gas. | change from operation to post-op second day (4 time) | |
Secondary | Glasgow Outcome Scale | Glasgow Outcome Scale; It is a scale developed to categorize people suffering from head trauma or non-traumatic acute brain injury into broad outcome categories. It shows postoperative mortality and morbidity of patients who underwent intracranial surgery. Glasgow Outcome Scale is a five-point scale. 1 point is considered death and five points as good recovery. As the score increases, morbidity and mortality decrease. | 30 days after the operation (1 time) |
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