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Clinical Trial Summary

This research study is studying a drug called Demeclocycline that may help brain surgeons see tumors with a microscope during surgery.


Clinical Trial Description

This research study is a Feasibility Study, which is the first time investigators are examining this study intervention.The FDA (the U.S. Food and Drug Administration) has not approved Demeclocycline for your specific disease but it has been approved for other uses.

In this research study, the investigators would like to determine the lowest dose of Demeclocycline that will allow surgeons to detect tumor cells during surgery. These cells will be marked through a process called fluorescence, which will cause tumor cells to glow brightly on an image in comparison to its surroundings. ;


Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Related Conditions & MeSH terms


NCT number NCT02740933
Study type Interventional
Source Massachusetts General Hospital
Contact William T Curry, MD
Phone 617-726-3779
Status Not yet recruiting
Phase Phase 1
Start date April 2016
Completion date January 2021

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