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Brain Natriuretic Peptide clinical trials

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NCT ID: NCT04238806 Completed - Cardiac Surgery Clinical Trials

Desflurane,Brain Natriuretic Peptide and Cardiac Surgery

Start date: September 1, 2013
Phase: N/A
Study type: Interventional

During coronary artery bypass grafting (CABG) operations with cardiopulmonary bypass (CPB), the use of desflurane continuously or intermittently may have effects on serum brain natriuretic peptide (BNP) levels. The aim is to investigate the association between desflurane, serum BNP values, and clinical outcomes during CABG operations. In a prospective, randomized, double-blinded study, desflurane inhalational anesthesia was administered either continuously or intermittently (Group 1; n=60 versus Group 2; n=62). The preoperative and postoperative BNP levels at 24, 48 and 72 hours after surgery were collected. Outcomes were recorded.

NCT ID: NCT03366857 Completed - Perioperative Clinical Trials

Effect of Supplemental Oxygen on Perioperative BNP Concentration in Cardiac Risk Patients

Start date: December 1, 2017
Phase: Phase 4
Study type: Interventional

The effect of supplemental oxygen on surgical site infections was already investigated in several studies before. Although, oxygen is one of the most used medical therapy in hospitalized patients, the influence on the cardiovascular system is still unknown. Available data indicate beneficial effects of supplemental oxygen on cardiovascular function. Because, no evidence exists concerning the perioperative period, it is our objective to investigate supplemental oxygen in cardiac risk patients undergoing major abdominal surgery. Due to the significant reduction of BNP by inhibiting sympathetic nerve activity we hypothesize that supplemental oxygen have beneficial effects in perioperative BNP release in cardiac risk patients undergoing major abdominal surgery.

NCT ID: NCT00368147 Completed - Clinical trials for Arteriovenous Fistula

Access Creation for Hemodialysis: Association With Structural Changes of the Heart

Start date: April 2002
Phase:
Study type: Observational

The purpose of this study is to determine if the creation of a fistula or a graft plays a role in the development of heart disease for patients undergoing hemodialysis