Intrafractional Head Movement During Radiosurgery

Status Completed

Clinical Trial Summary

This study investigates the intrafractional accuracy of a frameless thermoplastic mask used for head immobilization during stereotactic radiotherapy. Non-invasive masks cannot completely prohibit head movements. Previous studies attempted to estimate the magnitude of intrafractional inaccuracy by means of pre- and postfractional measurements only. However, this might not be sufficient to accurately map also intrafractional head movements.

Intrafractional deviation of mask-fixed head positions is measured in five patients during a total of 94 fractions by means of close-meshed repeated ExacTrac measurements conducted during the entire treatment session. From the obtained data the investigators evaluate the need to adjust safety margins around the gross tumor volume (GTV) whenever the investigated thermoplastic mask is used instead of invasive ring fixation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Brain Metastases, Adult

Clinical Trial Details

NCT number	NCT03896555
Study type	Observational
Source	Medical University Innsbruck
Contact
Status	Completed
Phase
Start date	November 1, 2014
Completion date	September 1, 2015

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05428852` - Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases	N/A
Recruiting	`NCT05559853` - Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment
Recruiting	`NCT05689619` - SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)	N/A
Recruiting	`NCT04197297` - Brain Imaging Biomarkers in Patients With Brain Metastasis	Phase 2
Recruiting	`NCT04397978` - Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases
Terminated	`NCT04434560` - Neoadjuvant Immunotherapy in Brain Metastases	Phase 2
Active, not recruiting	`NCT05095766` - Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis
Recruiting	`NCT05012254` - Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases	Phase 2
Recruiting	`NCT05789589` - Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases	Phase 1/Phase 2
Recruiting	`NCT06280300` - Multi-disciplinary Care for Brain Metastases	N/A
Recruiting	`NCT06047379` - Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis	Phase 1/Phase 2
Terminated	`NCT03789149` - Focal Intraoperative Radiotherapy of Brain Metastases	Phase 2
Recruiting	`NCT04343157` - UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases	Phase 2
Recruiting	`NCT04711824` - Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases	Phase 1/Phase 2
Recruiting	`NCT05793489` - Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin	N/A
Recruiting	`NCT04461418` - Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases	Phase 2
Recruiting	`NCT03818386` - Radiotherapy of Multiple Brain Metastases Using AGuIX®	Phase 2
Active, not recruiting	`NCT05087095` - Managing Distress in Malignant Brain Cancer	N/A
Recruiting	`NCT04396717` - Safety Study of Pritumumab in Brain Cancer	Phase 1
Recruiting	`NCT06231186` - a Feasibility Study of iHD-SRT for BM	N/A