Effects of Maternal Body Composition on Offspring Brain Structure and Function

Brain Function Clinical Trial

Official title:

Effects of Maternal Body Composition on Offspring Brain Structure and Function

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT01822067
• Other study ID #: 134776
• Status: Active, not recruiting
• Start date: August 2012
• Est. completion date: December 2024

Study information

• Verified date: December 2023
• Source: Arkansas Children's Hospital Research Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 100
• Est. completion date: December 2024
• Est. primary completion date: June 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 11 Days to 17 Days

Eligibility

Inclusion Criteria:

• the participant must be enrolled in the Arkansas Children's Nutrition Center (ACNC) Glowing study and be about 2 weeks of age +/- 3days

Exclusion Criteria:

• none specified

Related Conditions & MeSH terms

• Brain Function

Locations

Country	Name	City	State
United States	Arkansas Children's Nutrition Center	Little Rock	Arkansas

Sponsors (1)

Lead Sponsor	Collaborator
Arkansas Children's Hospital Research Institute

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Brain Structure	We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants	Age 2 weeks
Secondary	Brain Function	We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants	Age 2 weeks