Haemodynamical Optimization During Brain Surgery

Status Recruiting

Clinical Trial Summary

The decision to give fluids perioperatively could be based on methods used to identify preload responsiveness, either invasive or noninvasive estimates of stroke volume variation during mechanical ventilation. This study compares fluid management using invasive measurement SPV/PPV (Aisys GE) and noninvasive haemodynamic measurement (ClarSight, Edwards).

Clinical Trial Description

The aim of the study is to optimise fluid management and to reduce perioperative risks during brain surgery. Adequate perioperative management guided by hemodynamic monitoring can help to reduce the risk of complications and thus potentially improve outcomes. This study compares fluid management algorithms based either on invasive detection of fluid responsiveness using pulse pressure variation (PPV) and systolic pressure variation (SPV) values (Aisys GE monitoring system) in group A, or on noninvasive measurement of haemodynamics (stroke volume variation (SVV), cardiac index (CI) and systemic vascular resistance (SVR) values) (ClearSight, Edwards) in group B. ;

Study Design

Related Conditions & MeSH terms

Brain Edema

Clinical Trial Details

NCT number	NCT04114799
Study type	Interventional
Source	University Hospital Hradec Kralove
Contact	Vlasta Dostálová, MD, Ph.D.
Phone	777883571
Email	dostavla@seznam.cz
Status	Recruiting
Phase	N/A
Start date	April 1, 2019
Completion date	November 30, 2026

View Details

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