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Brain Concussion clinical trials

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NCT ID: NCT06365944 Recruiting - Brain Concussion Clinical Trials

Concussion in French Non-professional Handball League : Efficiency of a Concussion Protocol, the White Card Process

PRECCOCE
Start date: April 20, 2024
Phase:
Study type: Observational

Sport related concussion is a major issue for many contact sports, such as Rugby, Football, Hockey and Handball. As a response, some federations like World Rugby set up a concussion protocol, that starts with the referee having the responsibility to issue a blue card when suspecting a concussed player and thus have him off the field for medical examination. The French handball federation (FFHB) as well as its concussion protocol called "Protocole carton blanc", in this study we aim to describe the efficiency of this protocol.

NCT ID: NCT06340100 Recruiting - Clinical trials for Cognitive Impairment

Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes

Start date: March 23, 2024
Phase:
Study type: Observational

This study investigates the potential relationship between prior concussions and their impact on both vestibular function and cognitive abilities in athletes participating in sports.

NCT ID: NCT06328023 Recruiting - Sleep Clinical Trials

Impact of Concussion History on Sleep and Physical Performance in Contact Sports Athletes

Start date: March 18, 2024
Phase:
Study type: Observational

This study investigates the correlation between a history of concussions and its effects on both sleep patterns and physical performance among athletes engaged in contact sports. By examining the relationship between concussion history, sleep quality, and athletic performance, this research aims to provide insights into the potential long-term implications of concussions on the well-being and performance of athletes in contact sports

NCT ID: NCT06327776 Recruiting - Clinical trials for Mild Traumatic Brain Injury

New Protein Biomarkers and Technology for Improving Diagnosis and Outcome Prediction in Mild TBI

Start date: March 4, 2022
Phase:
Study type: Observational

Mild traumatic brain injury(mTBI) is a common cause of consultation to the emergency rooms worldwide and is the most common form of traumatic brain injury. Though classified as mild, as many as 40% of patients suffering mTBI do not make complete recoveries or present persistent symptoms. The present study is intended to determine long term outcome of patients suffering mTBI and to establish new prognostic models with the use of serum and saliva based biomarkers. For this purpose this study will not exclude patients regarding their comorbidities.

NCT ID: NCT06276660 Recruiting - Clinical trials for Mild Traumatic Brain Injury

Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test

Start date: March 5, 2024
Phase: N/A
Study type: Interventional

This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit.

NCT ID: NCT06270290 Recruiting - Concussion, Brain Clinical Trials

The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls

COSP-RBD
Start date: April 22, 2024
Phase:
Study type: Observational

The goal of this observational study is to investigate concussions and contact sports practices in REM sleep behaviour disorder (RBD). The main questions it aims to answer are: - What is the proportion of patients with RBD that have a history of concussions or exposure to contact sports? - Is this proportion higher to that in control patients without a diagnosis of RBD? Participants will undergo an interview with a sleep medicine specialist to answer questions about history of concussions and contact sports practices. Researchers will compare an RBD group and a control group (without RBD) to see if the proportion of concussions and exposure to contact sports differ.

NCT ID: NCT06260072 Recruiting - Clinical trials for Concussion, Intermediate

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Start date: February 10, 2020
Phase: Phase 2
Study type: Interventional

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

NCT ID: NCT06233851 Recruiting - Clinical trials for Mild Traumatic Brain Injury

t-BIOMAP : Prospective Paediatric Cohort Study of Blood Biomarkers in mTBI

t-BIOMAP
Start date: October 6, 2020
Phase:
Study type: Observational

The goal of this observational study is to identify blood biomarkers that could help in the management of paediatric patients with mild TBI. The main questions it aims to answer are: 1. How can blood biomarkers reduce unnecessary CT scan and reduce the length of stay at the emergency department? 2. How can blood biomarker predict post-concussion symptoms? Participants will have a blood sample taken when they are admitted at emergency department and will receive a questionnaire describing their symptoms 14 days and 3 months after their trauma.

NCT ID: NCT06222502 Recruiting - Clinical trials for Traumatic Brain Injury

Walking After Traumatic Brain Injury in Older Adults

Start date: January 16, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to test the effect of a planning, reminders, and micro-incentives intervention verses regular health education facts on physical activity participation over 12-weeks, in older adults who have previously suffered a non-penetrating mild or moderate TBI. Participants will provide information and be screened for eligibility via phone screening call (verification of age, confirmation that the participant is not currently on any medication that affects the central nervous system, and verification that the subject can participate in exercise, brief TBI history). Baseline testing will take place at the Center for Cognitive and Brain Health and Northeastern University Biomedical Imaging Center, for the baseline magnetic resonance imaging, in the interdisciplinary science and engineering complex on Northeastern University's campus. In person testing will take place over one session. The study period lasts 12 weeks, during which all participants will 1. Receive a weekly phone call with study staff, 2. Wear a wrist-worn Fit Bit tracker and 3. Record their weekly walking activities.

NCT ID: NCT06208813 Recruiting - Concussion, Brain Clinical Trials

Creatine Supplementation in Concussion Recovery

CSCR
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The proposed study aims to compare concussion recovery in those supplementing creatine and those not supplementing creatine. Specific aim 1: To compare number of days until asymptomatic between those taking creatine vs. those not taking creatine following a concussion. Hypothesis: The investigators hypothesize that individuals taking creatine will become asymptomatic sooner than those not taking creatine.Specific aim 2: To compare typical concussion assessment scores (i.e., symptom score, mental status, neurocognition, balance, motor coordination, and visual performance) between those taking creatine vs those not taking creatine following a concussion once asymptomatic.Hypothesis: The investigators hypothesize that individuals taking creatine will have better symptom scores, balance, mental status, and neurocognition assessment scores than those not taking creatine once asymptomatic. The investigators will calculate descriptive statistics for all demographic, days to asymptomatic, and concussion assessments. For specific aim 1, The investigators will calculate a t-test to determine if days to asymptomatic differed in those taking creatine vs. those not taking creatine. For specific aim 2, the investigators will calculate t-tests with Bonferonni corrections to determine if concussion assessment scores (Sport Concussion Office Assessment Tool-6 assessments, CNS Vital Signs, visual assessment) differed in those taking creatine vs. those not taking creatine.