Bradyarrhythmia Clinical Trial
Official title:
Mechanical and Electrical Dyssynchrony During His-Bundle Pacing (Selective and Non-selective) Versus His-Bundle Area Right Ventricular Pacing
The aim of this study is to evaluate mechanical and electrical cardiac dyssynchrony in patients with pacemakers and the right ventricular electrode implanted in His Bundle area.
Permanent His Bundle Pacing (HBP) is a well-known method of cardiac pacing which is increasingly used in everyday practice. After lead implantation in His Bundle area (HBA) capture of various tissues can be achieved: A. right ventricular myocardium near to HBP; B. cardiac conduction system selectively or nonselectively (with concomitant regional myocardium activation). The different excitability and refractory periods decide which tissue, myocardium or/and the conduction system is effectively paced. A lot of clinical trials revealed the advantage of HBP over apical ventricular pacing (AVP). HBP improves clinical (NYHA, quality of life, hospitalization rate) and echocardiographic (left ventricular dimension and ejection fraction) indicators of heart failure. We are going to compare mechanical and electrical synchrony during the various type of myocardium activation: HBP (nsHBP or sHBP), RV pacing near HBA and native heart rhythm (if possible) in each patient recruited to the study. Adequate pacemaker programming will allow achieving different activations as shown above. The mechanical synchrony will be estimated by transthoracic echocardiography and the electrical one by the detailed analysis of ECG. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00976482 -
Clinical Outcome of Pacemaker paTIents According to Pacing Modality and Primary INDications
|
N/A | |
| Completed |
NCT01089634 -
Left Ventricular Capture Management Study
|
||
| Completed |
NCT02930980 -
Micra Accelerometer Sensor Study 2
|
N/A | |
| Recruiting |
NCT03693157 -
The Safety and Efficacy of FFR Protocol in NTUH System
|
||
| Completed |
NCT05357716 -
Preliminary Research Evaluation for Ambulatory Leadless Electrocardiogram Recorder Trial
|
||
| Recruiting |
NCT05585411 -
PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial
|
N/A | |
| Completed |
NCT01513538 -
Analysis of the Acceptance and Changes to Parameters Programming Suggested by the TherapyGuide Function
|
N/A | |
| Completed |
NCT01522755 -
Predictive Factors of a Successful Implant of the CapsureFix MRI Model 5086
|
||
| Completed |
NCT05997004 -
Glycopyrrolate Prophylaxis for Prevention of Bradyarrhythmia During Laparoscopic Cholecystectomy
|
N/A | |
| Recruiting |
NCT04905199 -
Temporary Transvenous Pacemaker Placement by Intracavitary Electrocardiogram Monitoring
|
||
| Recruiting |
NCT05401851 -
Bi-ventricular Epicardial Activation in Left Bundle Area Pacing: a Comparison Study
|
N/A | |
| Not yet recruiting |
NCT04437901 -
COVIDAR - Arrhythmias in COVID-19
|
||
| Completed |
NCT01523704 -
Safety and Efficacy Study of IPG Patient With Home Monitoring
|
N/A | |
| Terminated |
NCT01535404 -
Right Versus Left Apical Transvenous Pacing for Patients With Preserved Left Ventricular Systolic Function Study
|
N/A | |
| Recruiting |
NCT06324682 -
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
|
||
| Completed |
NCT01715558 -
Clinical Outcome of Pacemaker paTIents According to Pacing Modality and Primary INDications OPTI-MIND 2
|
N/A | |
| Recruiting |
NCT01310907 -
Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia
|
N/A | |
| Recruiting |
NCT04831125 -
Conduction System Pacing International Registry (CONSPIRE)
|
||
| Completed |
NCT01897558 -
Myocardial Micro-damage in Relation to Active and Passive Fixation Pacemaker Electrodes
|
N/A |