BPH Clinical Trial
Official title:
Transurethral Resection Versus Transurethral Enucleation of the Prostate: Prospective Randomized Study
TUERP technique could be used in prostates of all sizes with the same safety and efficacy "size independent procedure" . TUERP could be performed using the bipolar system only ,with or without the use of morcellator.
Transurethral resection of the prostate (TURP) was first done in the 1920s. Since then, TURP has been considered as the gold standard treatment for BPH . However, its relatively high complication rate and postoperative recurrence necessitates further modification in the surgery technique .The resected adenomas have been reported to recur in up to 15% of cases that need a repeat surgical intervention, even by experienced surgeons in high-volume centers . Before the era of TURP, simple open prostatectomy was the mainstay of surgical therapy. However, open simple prostatectomy has high risk of considerable intraoperative bleeding requiring transfusion. The lower abdominal incision done in open prostatectomy may result in significant postoperative pain, an extended recovery period and longer hospital stay, with greater morbidity and a perioperative mortality rate of 0.2%. In addition, TURP for large prostatic adenomas causes significantly much more bleeding with clot retention as compared to simple open prostatectomy, it also need a longer operative time, which leads to increased risk of TUR syndrome with subsequent morbidity . A new technique in which transurethral enucleation and resection of the prostate (TUERP) was developed and adopted to replicate the open enucleation of prostatic adenomas in an endoscopic way. This will combine the benefits of complete prostate enucleation in a minimally invasive technique . prostate enucleation by laser currently used as minimally invasive and save alternative to TURP, but still has not been widely accepted for some reasons, including high cost and prolonged learning curve. TUERP technique could be used in prostates of all sizes with the same safety and efficacy "size independent procedure" . TUERP could be performed using the bipolar system only ,with or without the use of morcellator ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02974751 -
Global Post-Market Registry Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
|
||
Terminated |
NCT04398966 -
Prostatic Artery Embolization vs Medication for Benign Prostatic Hyperplasia
|
N/A | |
Completed |
NCT04029012 -
Penthrox in Rezūm BPH
|
Phase 4 | |
Recruiting |
NCT03912558 -
Pilot Study to Assess the Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in BPH Patients.
|
N/A | |
Completed |
NCT00527488 -
Explorative Study of Degarelix for Treatment of Benign Prostatic Hyperplasia.
|
Phase 2 | |
Recruiting |
NCT06323109 -
US Imaging for the Assessment of LUTS
|
||
Completed |
NCT05628025 -
Simulation-Based Enucleation Training: Initial Experience Using 3D-printed Organ Phantoms
|
||
Completed |
NCT00407329 -
Urokinase Plasminogen Activator System in Benign Prostatic Hyperplasia
|
N/A | |
Completed |
NCT00256399 -
Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)
|
N/A | |
Terminated |
NCT03994263 -
A Prospective Study to Observe the Mechanism of Action of the MediTate iTind in Subjects With Symptomatic BPH With MRI
|
N/A | |
Completed |
NCT03772808 -
Effects of LycoComfort™ Supplementation on Symptoms Associated With Lower Urinary Tract Symptoms (LUTS)
|
N/A | |
Completed |
NCT05818670 -
Comparison Between Tamsulosin and Tadalafil in Management of Benign Prostatic Hyperplasia Long Term Study
|
Phase 4 | |
Withdrawn |
NCT02961114 -
Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT04198103 -
Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia
|
N/A | |
Completed |
NCT00696761 -
The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients
|
Phase 4 | |
Completed |
NCT00199550 -
Bipolar vs Monopolar Transurethral Resection of the Prostate (TURP)
|
Phase 4 | |
Completed |
NCT02702947 -
Efficacy of Prunus Domestica Extract in BPH
|
Phase 4 | |
Completed |
NCT00154843 -
A Clinical Study to Determine Factors Affecting Absorption and Serum Levels of Lycopene After Supplementation
|
Phase 2 | |
Completed |
NCT00037141 -
Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate)
|
Phase 1/Phase 2 | |
Recruiting |
NCT05620784 -
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
|
Phase 3 |