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Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement

Hemophagocytic Lymphohistiocytosis Clinical Trial

Official title:
Efficacy and Safety of Segmental Resection Combined With the DEP Regimen for Epstein-Barr Virus Associated Hemophagocytic Lymphohistiocytosis With Intestinal Involvement

Clinical Trial Summary

EBV-HLH is a rare disease with high mortality, especially for those with intestinal involvement. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore the efficacy and safety of segmental resection combined with the DEP regimen.

Clinical Trial Description

Epstein-Barr virus associated hemophagocytic lymphohistiocytosis is a rare disease with high mortality, especially for those with intestinal involvement. Some of them still died despite early control of the disease due to severe complications, such as gastrointestinal bleeding. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore the efficacy and safety of segmental resection combined with the DEP regimen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06131489
Study type Observational
Source Beijing Friendship Hospital
Contact Zhao Wang, MD
Phone 63138303
Email wangzhao@ccmu.edu.cn
Status Not yet recruiting
Phase
Start date December 1, 2023
Completion date January 1, 2027
View Details
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