Clinical Trials Logo
  1. Home
  2. Bowel Preparation Solutions
  3. NCT01627171

Colonoscopy Preparation Optimization for INpatients- COIN Study — COIN  

Endoscopy Clinical Trial

Official title:
A Randomized Control Trial Comparing 4L PEGlyte to Regular Dose Pico-Salax and Split Dose Pico-Salax for Colonoscopy Bowel Preparation in Hospitalized Patients

Clinical Trial Summary

Colonoscopic examinations are performed routinely in hospitalized patients for a variety of indications. However, numerous limitations exist in hospitalized patients preventing an endoscopist from performing high quality examinations; possibly necessitating repeated procedures leading to increased cost and re-exposure to their inherent risks. One such prominent challenge lays in the adequacy of bowel cleansing. Inpatient status has been shown to be a predictor of poor bowel preparation as these patients are older, less mobile and have more co morbidities than the outpatient population. Currently, no standardized (or optimized) bowel preparation type or regimen for administration exists for the hospital inpatient population undergoing colonoscopy. Studies in the outpatient population have demonstrated that timing and choice of cathartic medication effects the cleanliness of the bowel preparation but there is no such clinical evidence for in-patients who receive whatever cathartic agent is on hospital formulary. The purpose of the study is compare efficacy, patient satisfaction, and adverse effects associated with low volume cathartic (Pico-Salax) to the current standard volume 4 liter (PEG-Lyte) and the effect of alternate timing of dosages.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01627171
Study type Interventional
Source St. Joseph's Healthcare Hamilton
Contact Lisa Balogh Melanson, BSc
Phone 905-522-1155
Email lbalogh@stjosham.on.ca
Status Recruiting
Phase Phase 4
Start date September 2012
Completion date December 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT03298776 - I-Scan a Novel Endoscopic Tool for the Macroscopic Identification of Mucosal Lesions N/A
Completed NCT02887378 - Protocol for Anatomopathologic Analysis of Biopsies Using Hot Clamps N/A
Completed NCT02350933 - Endoscopic Evaluation of the Paediatric Airway After Prior Prolonged (>24 h) Tracheal Intubation N/A
Completed NCT00671177 - Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique N/A
Completed NCT06033729 - Remifentanil Target Controlled Infusion Versus Standard of Care for Conscious Sedation During EBUS-TBNA N/A
Withdrawn NCT04983498 - Enhanced Recovery Pathway for Endoscopy Phase 4
Enrolling by invitation NCT04719117 - Retrograde Cholangiopancreatography AI Assisted System Validation on Effectiveness and Safety
Completed NCT03369197 - Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy N/A
Completed NCT04186390 - Learning Small Bowel Capsule Endoscopy
Completed NCT02714699 - Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy Phase 2/Phase 3
Completed NCT00614159 - Ketamine Compared to Propofol for Pediatric GI Endoscopy N/A
Completed NCT04072328 - Propofol vs. Midazolam With Propofol for Sedative Endoscopy in Patients With Previous Paradoxical Reaction to Midazolam Phase 2
Completed NCT04150237 - Using Simulation to Ensure Basic Competence in Gastroscopy
Completed NCT03287687 - Safety and Efficacy of CO2 for Endoscopy Phase 4
Not yet recruiting NCT03351790 - Endoscopy Quality Study N/A
Completed NCT04541667 - Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant N/A
Active, not recruiting NCT06168682 - Nasal CPAP - The Treatment IMpact on Oxygenation in High-risk Patients During Deep Sedation for Endoscopy N/A
Recruiting NCT05479253 - AI-assisted Endoscopy Report System In Improving Reporting Quality N/A
Recruiting NCT04903444 - Development and Validation of an Artificial Intelligence-based Biliary Stricture Navigation System in MRCP-based ERCP N/A
Recruiting NCT04809025 - Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer