Coffee After Pancreatic Surgery — COPS  

Postoperative Complications Clinical Trial

Official title: Coffee After Pancreatic Surgery - a Randomised, Single Blinded, Placebo-controlled Trial

Status Recruiting

Clinical Trial Summary

Postoperative ileus is a common complication after major abdominal surgery. A positive effect of coffee to bowel movement has been described after colorectal and gynecologic interventions. The objective of this randomised controlled trial is to investigate whether the implementation of a fast track protocol with early coffee consumption accelerates the recovery of bowel function after pancreaticoduodenectomy.

Clinical Trial Description

Postoperative ileus (POI) is a common disorder after major abdominal surgery, affecting up to 40% of patients undergoing laparotomy. POI is described as the time between surgery and the first passage of flatus and/or stool and tolerance of oral diet. It could be recognised as postoperative complication when is defined as two or more of nausea/vomiting, inability to tolerate oral diet over 24 h, absence of flatus over 24 h, abdominal distention and radiologic confirmation on or after day 4 postoperatively without prior resolution. Multimodal approaches have been described to treat POI; among them, the early consumption of coffee showed a substantial benefit after colorectal and gynecologic surgery. The objective of this randomised placebo-controlled trial is to investigate whether early coffee consumption can accelerate the recovery of bowel function after open pancreaticoduodenectomy. ;

Related Conditions & MeSH terms

• Bowel Dysfunction
• Intestinal Diseases
• Pancreatic Diseases
• Postoperative Complications
• Postoperative Ileus

• NCT number: NCT04205058
• Study type: Interventional
• Source: Azienda Ospedaliera Universitaria Integrata Verona
• Contact: Fabio Casciani, MD
• Phone: +39 045 8124553
• Email: fabio.casciani01@gmail.com
• Status: Recruiting
• Phase: N/A
• Start date: September 5, 2019
• Completion date: December 5, 2021