Bowel Cancer Clinical Trial
Official title:
Assessing Frailty and Its Impacts in Older Patients Facing Major Gastrointestinal Surgery
The study team will look at 3 new tests that will make it easier to measure frailty in patients awaiting surgery for cancer and compare them against standard clinical measures of frailty in a pilot study. The expected outcome is that evidence will be collated in order to apply for a major grant to look at improving the care of frail patients with cancer in the future.
Over 40% of patients with bowel cancer are over the age of 75. In older patients, rates of ill health and frailty are high, with frailty found in 6 in 10 patients over the age of 90. Surgery is the main treatment for bowel cancer, but the risks of surgery are higher in older people especially if they are frail. The main features of frailty are weight loss, lack of energy, weakness, slow walking speed and low activity levels. Frailty is a condition linked to an increased risk of death and major complications after surgery. As a result, older and frailer patients are often refused surgery for their cancer. If we could identify frailty more reliably before surgery, we could offer patients better counselling about the surgical risks and benefits. We could also offer treatments that might improve their fitness, making the surgery safer (pre-operative exercise, better post-operative support). Surgeons are not very good at measuring frailty because the clinical tests for it are complicated and take a long time to complete. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05110378 -
Do Good Non-Technical Skills Correlate With Good Clinical Outcomes in Endoscopy?
|
||
| Completed |
NCT05032794 -
Unrestricted Diet for Screening Colonoscopy
|
N/A | |
| Completed |
NCT04659590 -
Exploratory Study of Rectal Mucus for Diagnosing Disease
|
||
| Completed |
NCT05043363 -
LuCID - Investigating the Use of a Novel Digital Rectoscope for Community Examinations During COVID-19
|
||
| Recruiting |
NCT06106165 -
Improving Muslim Women's Uptake of Cancer Screening (IMCAN)
|
N/A | |
| Completed |
NCT03479645 -
Serial SMS Reminders and an Opt-out Mailed FIT Kits to Improve Colorectal Screening Participation: A Single Center RCT
|
N/A | |
| Not yet recruiting |
NCT06219395 -
Capsule Endoscopy in Iron Deficiency Anaemia
|
||
| Completed |
NCT02208401 -
Randomised Comparison of 2 Cold Snare Polypectomy Techniques
|
N/A | |
| Recruiting |
NCT06008847 -
Capsule Endoscopy Delivery at sCale Through Enhanced AI anaLysis Study
|
||
| Enrolling by invitation |
NCT02662348 -
T Cell Mediated Adaptive Therapy for Her2-positive Neoplasms of Digestive System
|
Phase 1 | |
| Recruiting |
NCT04747665 -
Experiences and Perceptions of Colonoscopy and New Technologies
|
||
| Recruiting |
NCT02633098 -
A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer
|
Phase 2 | |
| Completed |
NCT01868971 -
Clinical Study to Establish the Feasibility and Usability of the EndoRings™
|
N/A | |
| Recruiting |
NCT03563586 -
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
|
N/A |