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Bone Neoplasms clinical trials

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NCT ID: NCT06376539 Not yet recruiting - Rehabilitation Clinical Trials

Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.

FISIO-ONCO
Start date: May 2024
Phase:
Study type: Observational

The aim of the present study is to describe the course of functional recovery of patients with musculoskeletal tumours and undergone resection and reconstruction operations of lower limbs in the first six months post-surgery, differentiating them on the basis of the anatomical level involved.

NCT ID: NCT06235034 Not yet recruiting - Bone Metastases Clinical Trials

Diagnostic CT Palliative Radiotherapy: Feasibility Study of Treating Bone Metastases Without a CT Simulation

dCT-PRT
Start date: January 20, 2024
Phase: N/A
Study type: Interventional

The purpose of this non-randomized, prospective study is to assess the feasibility of planning and delivering conventional palliative radiotherapy to bone metastases on previously available diagnostic CT scans (dCT). Objectives:1) dosimetric accuracy of palliative radiotherapy designed on a dCT compared to a CT simulation 2) assess suitability of patient set up using surface landmarks and kilo voltage (kV) imaging 3) determine the proportion of patients who can receive radiotherapy designed on a dCT 4) confirm eligibility criteria for appropriate patients in clinical practice All enrolled patients will undergo a CT simulation with tattoos as per current standard of care.The radiation oncologist will place fields on the dCT and CT simulation. Radiotherapy will be planned on both CT scans and reviewed for quality by both the radiation oncologist and medical physicist.

NCT ID: NCT06221072 Not yet recruiting - Clinical trials for Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

Start date: April 5, 2024
Phase: Phase 3
Study type: Interventional

This is a phase Ⅲ, multicenter, randomized, double-blind, study to evaluate the efficacy and safety of JMT103 in patients with bone metastases from malignant solid tumors. The purpose of this study is to determine if JMT103 is non-inferior to zoledronic acid.

NCT ID: NCT06070259 Not yet recruiting - Bone Cancer Clinical Trials

Insights Into Participating in Studies for Bone Cancer

Start date: October 2024
Phase:
Study type: Observational

Clinical studies, with a distinct focus on bone cancer, play a crucial role in evaluating the safety and effectiveness of novel treatments for this disease. These trials serve as instrumental means to determine whether new medications surpass conventional therapies, providing substantial evidence for their broader adoption. The primary objective is to meticulously scrutinize trial completion rates and voluntary withdrawals within this specific patient group.

NCT ID: NCT05813665 Not yet recruiting - Clinical trials for Giant Cell Tumor of Bone

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Start date: April 2023
Phase: Phase 3
Study type: Interventional

This is a phase Ⅲ, multi-center, randomized, double-blind, active-controlled study to evaluate the efficacy and safety of narlumosbart (JMT103) in patients with unresectable or surgically difficult giant cell tumor of bone (GCTB). This clinical trial study hypothesizes narlumosbart administration groups are not inferior to active control administration groups.

NCT ID: NCT05730972 Not yet recruiting - Clinical trials for Non Small Cell Lung Cancer

TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

This multicenter, prospective, randomized controlled research study aims to objectively evaluate the role of transcutaneous electrical acupoint stimulation (TEAS), which combines the theory of acupuncture with transcutaneous electrical nerve stimulation (TENS) therapy, for the treatment of pain in patients with bone metastases from lung cancer.

NCT ID: NCT05665790 Not yet recruiting - Bone Metastases Clinical Trials

Primary Lesion Treatment for Bone Metastases

Start date: March 2023
Phase: N/A
Study type: Interventional

This study will carry out a prospective cohort study to study the effect of different primary leison treatment modes on disease control, quality of life, economic cost and survival period of patients with bone metastases from breast cancer and lung cancer by giving radiotherapy or palliative surgery or not giving local treatment for the primary lesion in patients with bone metastases from breast cancer or lung cancer

NCT ID: NCT05665439 Not yet recruiting - Bone Metastases Clinical Trials

Local Treatment for Bone Metastases

Start date: March 2023
Phase: N/A
Study type: Interventional

This study will carry out a prospective randomized controlled study to study the effect of different local treatment on disease control, quality of life, economic cost and even survival period of patients by randomly giving local radiotherapy or observation to patients with newly diagnosed bone metastases or patients with bone metastases after vertebroplasty.

NCT ID: NCT05616195 Not yet recruiting - Malignant Tumor Clinical Trials

Application of 3D Printed Prosthesis in Limb Salvage Surgery for Bone Tumors

Start date: December 28, 2024
Phase:
Study type: Observational

To report the patients who underwent 3D-printed bone prosthesis replacement in Henan Cancer Hospital in the next 10 years, and collect the postoperative complications and limb function of these patients.

NCT ID: NCT05598229 Not yet recruiting - Clinical trials for Perioperative Period

Application of Douyin in Perioperative Period of Malignant Tumor Patients

Start date: December 28, 2024
Phase: N/A
Study type: Interventional

Fitting into the group of 90 cases of this study was to henan tumor hospital bone prosthesis replacement of surgical treatment of bone malignant tumors patients, evaluate watch trill to be bone prosthesis replacement surgery treatment of malignant bone tumor patients perioperative anxiety, depression, pain, explore watch trill to bone prosthesis replacement surgery treatment of malignant bone tumor patients of postoperative complications.