Clinical Trials Logo
  1. Home
  2. Bone Neoplasm
  3. NCT00841152

Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute — BAGvsTCP  

Bone Neoplasm Clinical Trial

Official title:
A National, Prospective, Randomized, Multicenter, Controlled Head-to-Head Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute in Filling of Contained Bone Defects

Clinical Trial Summary

This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone defects following surgical evacuation of benign bone tumor or tumor-like conditions. Based on the investigators' previous preclinical research and an ongoing single-center randomized clinical trial on bioactive glass filling, the investigators expect BAG filling to be more efficient compared to TCP in promotion of defect healing and functional recovery after surgery.

Clinical Trial Description

This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone defects following surgical evacuation of benign bone tumor or tumor-like conditions. Small metacarpal and phalangeal enchondromas (Stratum I) and large long-bone lesions (Stratum II) will be evaluated separately. Aside with the head-to-head comparison of the two synthetic bone graft substitutes, autologous bone graft (Stratum I) and allogeneic bone graft (Stratum II) will be used as the standard of care controls. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00841152
Study type Observational
Source Turku University Hospital
Contact
Status Completed
Phase
Start date March 2009
Completion date December 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT03072186 - Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery N/A
Not yet recruiting NCT06376539 - Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.
Recruiting NCT03129672 - Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle
Not yet recruiting NCT03106675 - MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases N/A
Completed NCT04884048 - Multicentric Bone Tumor Imaging Report and Data System
Recruiting NCT04307914 - Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases N/A
Withdrawn NCT00478270 - A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease. Phase 2
Recruiting NCT04394052 - Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II
Terminated NCT00099203 - A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease Phase 3
Completed NCT05881343 - Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery
Recruiting NCT05310539 - Early Recovery After "Wedge Resection" Surgery to Remove Lung Mestastasis Secondary to Bone Cancer.
Active, not recruiting NCT03678883 - 9-ING-41 in Patients With Advanced Cancers Phase 2
Recruiting NCT03442465 - Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
Terminated NCT00099177 - A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain Phase 3
Completed NCT04074291 - Cross Cultural Validation of the Italian Version of the Bt-DUX
Completed NCT04310410 - Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis Phase 1/Phase 2