Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration

Status Not yet recruiting

Clinical Trial Summary

Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.

Clinical Trial Description

During cyst enucleation , There's resultant decrease in bone density especially in large defects .Therefore, it may be needed for a bone grafts and bone regenerative materials to improve quality of bone .The rationale is to evaluate hyaluronic acid with hydroxyapatite as a bone quality improvement material following cyst enucleation, which would provide significant bone regeneration. Hydroxyapatite is inorganic component of bone tissue used as bone graft, scaffolds, filler and cement for repair and regeneration of bone defect , and it is stimulate bone remodeling by generating surface active moieties or cell signaling process while Hyaluronic acid and it's derivatives has been widely used for bone regeneration and it has a good potential for osteogenesis and mineralization ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05957926
Study type	Interventional
Source	Cairo University
Contact	Enas Eldaour, BSc.
Phone	01016676513
Email	enas.fadel@dentistry.cu.edu.eg
Status	Not yet recruiting
Phase	N/A
Start date	October 1, 2023
Completion date	January 1, 2025

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