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BONE: STAR (Switching to TAF Based Anti-Retroviral Therapy) Study — BONE:STAR  

Bone Loss Clinical Trial

Official title:
A Phase IV Open-Label Trial to Assess Bone Mineral Density in a Cohort of African Women on Depo-provera and Tenofovir Disoproxil Fumurate Switched to Tenofovir Alafenamide Fumarate Based Anti-Retroviral Therapy

Clinical Trial Summary

The primarily objective of this study is to assess the effect of switching from Tenofovir Disoproxil Fumurate (TDF) to TAF based ART on bone mass and turnover among women on DMPA for contraception. HIV virologically suppressed women on DMPA will be switched from their TDF based regimen to Bictergravir /Emtricitabine / Tenofovir alafenamide (B/F/TAF; Biktarvy®) in a randomized fashion. HIV infected women on TDF and non-hormonal contraception will be switched to Biktarvy®).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03916328
Study type Interventional
Source MU-JHU CARE
Contact Judith Mbanza, MA
Phone +256414541044
Email jmbanza@mujhu.org
Status Recruiting
Phase Phase 4
Start date December 3, 2019
Completion date March 31, 2024
View Details
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