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An Intervention Study to Investigate the Effect of B-vitamin Supplementation for 2-years on Bone Health — Opti-Age  

Bone Health Clinical Trial

Official title:
A Randomised Controlled Trial to Investigate the Effect of Combined B-vitamin Supplementation for 2-years on Bone Mineral Density in Older Irish Adults With Sub-optimal B-vitamin Status

Clinical Trial Summary

An intervention study to investigate the effect of B-vitamin supplementation for 2-years on bone health. This is a dual centre (UCD and University of Ulster) 2-year randomised, placebo controlled, double blind intervention.

Clinical Trial Description

Osteoporosis is a major public health issue, especially among older adults. The condition is widespread, with an estimated 1 in 2 women and 1 in 5 men over the age of 50 years expected to have an osteoporotic fracture. The associated health care costs are considerable and growing as the population of older adults increases. Furthermore, osteoporotic fractures are associated with loss of independence and risk of further fractures and health problems for the individual. Given these negative impacts, new approaches to help maintain better bone health in older age are urgently needed. Vitamin D and calcium have well established protective roles, however, other evidence links certain B vitamins with bone health. This study will investigate the effect of B-vitamin supplementation over a two year period at two centres (UCD and University of Ulster) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03892395
Study type Interventional
Source University College Dublin
Contact
Status Completed
Phase N/A
Start date May 5, 2017
Completion date May 31, 2022
View Details
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