Socket Preservation Using Autogenous Bone Graft Versus MPM

Bone Graft; Complications Clinical Trial

Official title:

Dental Implant Placement in Extraction Socket of Mandibular Anterior and Premolar Areas Treated With Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03008538
• Other study ID #: CairoSPR-Aut
• Status: Active, not recruiting
• Phase: Phase 1/Phase 2
• First received: December 26, 2016
• Last updated: December 30, 2016
• Start date: September 2016
• Est. completion date: December 2017

Study information

• Verified date: December 2016
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Egypt: Ministry of Higher Education
• Study type: Interventional

Clinical Trial Summary

Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.

Description:

To assess bone quality, stability of implants placed in fresh extraction sockets of mandibular anterior and premorals augmented by MPM (Mineralized Plasmatic Matrix) versus autogenous bone graft (gold standard), at different follow-up periods (0, 3, 6, 9 months).

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 20
• Est. completion date: December 2017
• Est. primary completion date: September 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

1. Medically free patients.

2. Patients with mandibular anterior and premolar hopeless teeth indicated for extraction.

3. Evaluated bone height on X.Ray to be (0-4 mm buccal bone dehiscence).

4. Age between 18 and 40 years.

5. Both sexes.

6. Patients physically able to tolerate surgical and restorative procedures. Good oral hygiene.

7. Highly motivated patients.

Exclusion criteria:

1. Smokers.

2. Pregnant or lactating females.

3. Presence of any pathosis in the pre-implant site.

4. Presence of Para functional habits.

5. History of oral radiotherapy.

6. History of prolonged steroids use

7. Psychological disorders.

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Bone Graft; Complications

Intervention

Other:
• MPM(Mineralized plasmatic matrix).
Preparation of sticky bone graft by addition of growth factors obtained from patient's vebous blood.
• Autogenous Bone Graft
Socket preservation using autogenous bone graft for preservation of bone width and height for future implant insertion.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Patient Satisfaction regarding function, to be measured using patient questionnaire.		3 Months.	Yes
Secondary	Comparative histomorphometric analysis, to be measured using a digital software called (leica QWin 500) and unit of measurements are to be (Pixels).		3 Months.	Yes