Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies.

Bone Disorder Clinical Trial

— OSCAR  

Official title:

Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06444503
• Other study ID #: RC31/24/0214
• Status: Not yet recruiting
• Start date: August 2024
• Est. completion date: August 2034

Study information

• Verified date: May 2024
• Source: University Hospital, Toulouse
• Contact: Thomas EDOUARD, MD
• Phone: 05 61 77 61 10
• Email: edouard.t[@]chu-toulouse.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.

This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 350
• Est. completion date: August 2034
• Est. primary completion date: August 2034
• Accepts healthy volunteers: No
• Gender: All
• Age group: 0 Years to 99 Years

Eligibility

Inclusion Criteria:

• Children (from birth) with growth plate or bone pathology

• Patients affiliated to or benefiting from a social security scheme

• Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :

• mastery of the French language

• Not being subject to a restriction of rights by the judicial authorities

• Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).

Exclusion Criteria:

• Patients under legal protection (guardianship, curatorship or safeguard of justice)

• Pregnant or breast-feeding women

Related Conditions & MeSH terms

• Bone Diseases
• Bone Disorder

Intervention

Other:
• Biological
Blood and urine will be taken in larger quantity
• Biological
Surgical residues may be preserved in the event of surgery carried out as part of the treatment.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Toulouse

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies	Blood and urine sampling	Day 0 and through study completion, an average of 5 years
Secondary	Identification of potential markers of disease progression based on new knowledge.		Day 0 and through study completion, an average of 5 years