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Bone Disease, Metabolic clinical trials

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NCT ID: NCT06184646 Recruiting - Clinical trials for Bone Disease, Metabolic

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.

NCT ID: NCT03386981 Recruiting - Physical Activity Clinical Trials

Metabolic Profile of Bone in Professional Athletes

SportMarkers
Start date: February 4, 2016
Phase: N/A
Study type: Observational

Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.

NCT ID: NCT03169192 Not yet recruiting - Clinical trials for Bone Disease, Metabolic

Diagnosis of Osteogenesis Imperfecta in Children

Start date: June 1, 2017
Phase: N/A
Study type: Observational

The study will be conducted at Assiut university children hospital and it will include patients with history of repeated fractures due to mild or irrelevant trauma. Diagnosis will be established by biochemical tests, bone survey to exclude secondary causes followed by Dual Energy absorbiometry scan to detect bone density of selected cases then confirm our diagnosis by detection of gene mutations of Osteogenesis imperfecta during one and half year duration with starting zoledronic acid therapy during this duration.

NCT ID: NCT02731820 Completed - Osteopenia Clinical Trials

Efficacy of Potassium Citrate in the Treatment of Postmenopausal Osteopenia

ACAROS
Start date: September 1, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether the use of alkali compounds, i.e. potassium citrate (K3C6H5O7, hereinafter KCitr) is effective in preventing the progression of osteopenia. A randomized clinical trial (RCT, placebo-controlled, double-blind) has been planned to evaluate the effect of the daily administration of KCitr (3 g/die, K 30 mEq). The efficacy will be evaluated by comparing the circulating levels of bone turnover markers at the baseline and after the treatment (3, 6 months).

NCT ID: NCT00657852 Completed - Clinical trials for Bone Disease, Metabolic

Efficacy of Pamidronate in the Treatment of Bone Loss Associated With Liver Transplant

Start date: December 2000
Phase: Phase 4
Study type: Interventional

The aims of this study are to prospectively evaluate the efficacy of two intravenous infusions of pamidronate 90 mg, associated with calcium and calcidiol, in the early post-transplant period, on bone loss in liver transplant recipients, and to asses the safety of this treatment.

NCT ID: NCT00067834 Completed - Osteopenia Clinical Trials

Electromagnetic Treatment For Bone Loss After Forearm Fracture

Start date: November 2003
Phase: Phase 1/Phase 2
Study type: Interventional

This study will determine the usefulness of pulsing electromagnetic field (PEMF) technology to reverse or reduce the bone loss (osteopenia) that occurs in the forearm after fracture or surgery.