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Bone Cyst Aneurysmal clinical trials

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NCT ID: NCT03415477 Completed - Recurrent Disease Clinical Trials

Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts

Deno-ABC
Start date: January 1, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The efficacy of traditional therapeutic approaches for aneurysmal bone cysts (ABC), such as surgery, embolization, sclerotherapy and radiotherapy, are often compromised for lesions in axial skeletons and adolescents complicated with pathological fracture. Therefore, denosumab, a new drug that has been successfully used in giant cell tumor of bone but has seldom used in ABC, was used to treat ABC in this trial.