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Massive Implants the Next Generation — MING  

Bone Diseases Clinical Trial

Official title:
A Randomised, Single Blind Study Assessing Radiological Outcomes for Massive Segmental Femoral Replacements Using Either Porous Collar or Porous Collar With HA or Porous Collar With HA and Autologous Stem Cells

Clinical Trial Summary

The study will review the use of massive segmental replacements in the femur, which have a porous collar with and without HA, and autologous stem cell augment. This is a randomised controlled trial.

Clinical Trial Description

The current surgical treatment of bone cancer patients and revision limb salvage requires usage of massive endoprosthetic bone implants. The incidence of aseptic loosening is a major cause of prosthesis failure in these patients, exploring ways to reduce such failures would allow extending longevity of massive implants in a relatively young population. Current published literature stipulates that osteointegration could improve longevity of massive implants. Evidence suggests that usage of osteointegrated hydroxyapatite (HA) coated collar would reduce the incidence of aseptic loosening around the cemented intramedullary stem in distal femoral bone prosthesis ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03905174
Study type Interventional
Source Royal National Orthopaedic Hospital NHS Trust
Contact Panos Gikas, PhD FRCS
Phone 02089092300
Email rnoh.research@nhs.net
Status Recruiting
Phase N/A
Start date September 20, 2018
Completion date December 31, 2024
View Details
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