HLA Sensitization Following Major Cortical Allograft Bone Procedures

Status Completed

Clinical Trial Summary

The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone.

Clinical Trial Description

Patients who have bone cancer often have the cancerous bone removed by surgery and replaced with a piece of bone taken from a donor (a person who donates parts of their body to be used for transplants after their death). However, sometimes this replacement bone does not heal together with the patient's bone. The reason the bone does not heal is not known but it is thought that the patient's body may react to the donor bone by producing antibodies against cells on the donor bone. The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone. You have been asked to participate in this study because you are scheduled to undergo this type of surgery. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Bone Cancer

Clinical Trial Details

NCT number	NCT00160719
Study type	Observational
Source	University of Florida
Contact
Status	Completed
Phase	Phase 4
Start date	September 1999
Completion date	March 2010

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