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Clinical Trial Summary

The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as a bone filler containing the patient's own (autologous) adipose (fat) tissue-derived cells in reconstructing bone in two clinical indications: 1. Bone augmentation (e.g. sinus augmentation) 2. Bone grafting after removal of cysts from jaws


Clinical Trial Description

Primary endpoint: The transplantation of BonoFill-II to the maxillary or mandible defect/void is safe under the following conditions: No chronic bone infection (Osteomyelitis); no significant changes in complete blood count (CBC) and in general health. Secondary endpoint: The transplantation of BonoFill-II to the maxillary or mandible void is efficient under the following conditions: Following BonoFill-II implantation, the bone regeneration in the operated site was significantly accelerated. Also, the bone defects/voids were filled with a significant amount of bone tissue. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02842619
Study type Interventional
Source BonusBio Group Ltd
Contact Ephraim Tzur, DMD
Phone 972-53-734-5356
Email drefitzur@gmail.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 23, 2016
Completion date December 30, 2022

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