Clinical Trials Logo
  1. Home
  2. Bone Augmentation
  3. NCT02842619

Filling Bone Defects/Voids With Autologous BonoFill-II for Maxillofacial Bone Regeneration

Bone Augmentation Clinical Trial

Official title:
Phase I/II Open Label First in Human Single Center Clinical Study Aimed to Evaluate the Safety and Efficacy of BonoFill-II in Reconstructing Maxillofacial Bone

Clinical Trial Summary

The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as a bone filler containing the patient's own (autologous) adipose (fat) tissue-derived cells in reconstructing bone in two clinical indications: 1. Bone augmentation (e.g. sinus augmentation) 2. Bone grafting after removal of cysts from jaws

Clinical Trial Description

Primary endpoint: The transplantation of BonoFill-II to the maxillary or mandible defect/void is safe under the following conditions: No chronic bone infection (Osteomyelitis); no significant changes in complete blood count (CBC) and in general health. Secondary endpoint: The transplantation of BonoFill-II to the maxillary or mandible void is efficient under the following conditions: Following BonoFill-II implantation, the bone regeneration in the operated site was significantly accelerated. Also, the bone defects/voids were filled with a significant amount of bone tissue. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02842619
Study type Interventional
Source BonusBio Group Ltd
Contact Ephraim Tzur, DMD
Phone 972-53-734-5356
Email drefitzur@gmail.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 23, 2016
Completion date December 30, 2022
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04367766 - Management of the Fresh Extraction Socket in the Aesthetic Area N/A
Completed NCT02154386 - Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft N/A
Completed NCT05612737 - Evaluation of a Novel Horizontal Ridge Augmentation Technique in Dentistry N/A
Completed NCT04775940 - Use of Perforated Barrier Membranes and IPRF Nano- Micro Sticky Bone N/A
Not yet recruiting NCT02998632 - Posterior Mandibular Ridge Augmentation Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft N/A
Active, not recruiting NCT06140277 - Using Of Chitosan in Alveolar Ridge Preservation Phase 2
Active, not recruiting NCT05339971 - Modified Surgical Technique for Lateral Block Augmentation Prior to Implant Installation N/A
Not yet recruiting NCT02406924 - Bone Augmentation Using Particulated Biomaterial and Autogenous Bone, Stabilized by Collagen Membrane and Pins (PaMP) N/A
Completed NCT04462575 - Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane N/A