Bone Augmentation Using Calvarial Versus Iliac Crest Bone Blocks.

Bone Atrophy Clinical Trial

Official title:

Radiographic Assessment of Horizontal Bone Augmentation of Full Atrophic Maxillary Alveolar Ridges Using Calvarial Versus Iliac Crest Bone Blocks:

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06434441
• Other study ID #: 13
• Status: Recruiting
• Phase: N/A
• Start date: August 10, 2023
• Est. completion date: June 1, 2024

Study information

• Verified date: May 2024
• Source: Beni-Suef University
• Contact: Amr Gibaly
• Phone: 01113336634
• Email: amrgibaly[@]dent.bsu.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims to evaluate and compare the quantity of the radiographic horizontal bone gain of severely deficient complete maxillary ridges reconstructed by bone block harvest from the iliac crest versus the calvarial bones

Description:

Although the calvarial bones represent a nearby donor site for maxillary augmentation of matching bone origin, the excessive volume of bone needed to reconstruct a severely deficient arch, the limited cancellous bone volume, and the arciform pattern of the skull cap that yield the curvatures of the harvested cortical blocks incompatible with the topography of the maxillary arch, all represent limitations for the calvarial graft.

The anterior iliac crest is frequently used for free bone grafting by being subcutaneous and generous to afford ample bone blocks of favorable curvatures. However, the minute cortical overlay and its endochondral origin contribute to excessive graft resorption. Pikos et al. demonstrated that a reasonable amount of graft resorption could occur with atraumatic surgical intervention and intimate graft fixation.

This study aims to evaluate and compare the quantity of the radiographic horizontal bone gain of severely deficient complete maxillary ridges reconstructed by bone block harvest from the iliac crest versus the calvarial bones.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 10
• Est. completion date: June 1, 2024
• Est. primary completion date: June 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 55 Years

Eligibility

Inclusion Criteria:

• Patients with the clinical and radiographic interpretation of horizontal maxillary ridge deficiency of less than 5 mm

Exclusion Criteria:

• Any previous maxillary reconstructive or dental implant treatment.

• Any local pathologic lesion or systemic disease that would affect the typical pattern of bone healing.

Related Conditions & MeSH terms

• Atrophy
• Bone Atrophy

Intervention

Procedure:
• Autogenous bone augmentation
Maxillary alveolar bone reconstruction

Locations

Country	Name	City	State
Egypt	Amr Gibaly	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Beni-Suef University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Horizontal bone gain	the study compares the horizontal bone gain of reconstructed maxillary alveolar ridges after being augmented with calverial and iliac crest bone grafts radiographically by millimeters	6 months consolidation period
Secondary	Immunohistochemical bone formation	the study compares the bone area percent of the consolidated calverial and iliac crest bone grafts	6 months consolidation period