Clinical Trials Logo
  1. Home
  2. Body Weight Changes
  3. NCT01608698

Comparison of Body Weight Change During Contraception With Belara and Yasmin

Body Weight Changes Clinical Trial

Official title:
A Comparison of Body Weight Changing and Side Effects Between Treatment With 30 mcg Ethinylestradiol/2 mg Chlormadinone Acetate (Belara®) and 30 mcg Ethinylestradiol/3 mg Drospirenone (Yasmin®): A Randomized Control Trial

Clinical Trial Summary

The purpose of this study is to evaluate different side effect in contraceptive use of two oral combined contraceptive pills (OCP)in combination of 30 mcg ethinylestradiol/2 mg chlormadinone acetate (Belara®) and 30 mcg ethinylestradiol/3 mg drospirenone (Yasmin®), especially body weight change.

Clinical Trial Description

Oral combined contraceptive pills (OCP) is the most contraceptive use in reproductive women. The various type of progestins in OCP give various effects either benefit (non-contraceptive benefit) and side effect. These effects depend on pharmacological activity of each progestin. Many studies showed causes of discontinuation use of OCP, such as increase body weight,androgenic effect and vaginal spotting. OCP in combination of 30 mcg ethinylestradiol/2 mg chlormadinone acetate (Belara®) and 30 mcg ethinylestradiol/3 mg drospirenone (Yasmin®)are the common used in practice. The each type of progestin (chlormadinone and drospirenone) might effect different outcomes in women especially in body weight change during use. Chlormadinone is a C-21 progestin which has glucocorticoid and antiandrogenic effect. Drospirenone is a progestin in spironolactone derivative which has antimineralocorticoid and antiandrogenic effect. Both progestins might has less effect in body weight change and provide other non-contraceptive benefits. So investigator want to study the different effects from these progestin in two type of OCP. The result from this study could give information to choose the proper OCP for each reproductive woman. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01608698
Study type Interventional
Source Mahidol University
Contact
Status Enrolling by invitation
Phase Phase 4
Start date June 2012
Completion date February 2016
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04578067 - Empowering Immigrant Women for Active and Healthy Lifestyle N/A
Completed NCT02229708 - Targeting Pregnancy-related Weight Gain to Reduce Disparities in Obesity N/A
Completed NCT00065052 - Modifying the Home Television Watching Environment N/A
Completed NCT04340388 - Contribution of Dolutegravir to Obesity and Cardiovascular Disease Phase 4
Completed NCT04997447 - Enforced Reduction in Physical Activity and Recovery in Older Adults N/A
Active, not recruiting NCT03843424 - Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers N/A
Completed NCT04559542 - Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes
Recruiting NCT04554758 - Comparative Analysis Between Sleeve Gastrectomy and Roux-en Y Gastric Bypass in Bariatric Operation N/A
Recruiting NCT06078150 - Effects of Active Video Games on Chinese Overweight and Obese College Students' Physical and Mental Health N/A
Recruiting NCT02966444 - Hunger, Satiety, and Metabolic Responses to High-fat Meals of Varying Fatty Acid Composition N/A
Completed NCT01061346 - Effect of Dietary Fat When Eaten With Fructose Versus Glucose N/A
Recruiting NCT03917758 - Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors N/A
Completed NCT06132269 - Evaluation the Effect of AKK Formula on Intestinal Microbiota Regulation and Body Composition N/A
Completed NCT03524521 - Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults N/A
Active, not recruiting NCT02737267 - Development of a Nutrigenetic Test for Personalized Prescription of Body Weight Loss Diets (Obekit) N/A
Completed NCT02554318 - Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia N/A
Completed NCT01820702 - Short Term Bed Rest Study: Evaluation of the Use of Artificial Gravity, Induced by Short-arm Centrifugation N/A
Completed NCT03480464 - App-technology to Improve the Level of Physical Activity After Bariatric Surgery N/A
Completed NCT03372109 - Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain N/A
Completed NCT03283657 - Diabetes Risk Education and Communication Trial N/A