Body Dysmorphic Disorders Clinical Trial
Official title:
Safety and Efficacy of Psilocybin for Body Dysmorphic Disorder
In this pilot study 12 adult outpatients with body dysmorphic disorder that has not responded to at least one adequate trial of a serotonin reuptake inhibitor will be treated openly with a single oral dose of psilocybin. Followup visits to monitor safety and clinical outcome will be conducted over a 3 month period.
In this pilot study, up to 12 adult outpatients with body dysmorphic disorder that has not responded to at least one adequate trial of a serotonin reuptake inhibitor will be treated openly with a single oral dose of psilocybin. Procedures will follow those previously established in depression studies of psilocybin. Patients will receive intensive preparation and support from two therapists, including 8-9 hours accompanying the patient on the day of medication administration in the Biological Studies Unit of New York State Psychiatric Institute. Followup visits to monitor safety and clinical outcome will be conducted at day 1, week1, and months 1,2, and 3 post-administration. Resting state function magnetic resonance imaging will be conducted prior to and one day after psilocybin administration to assess the effect of medication on brain circuits. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02524301 -
Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study
|
N/A | |
| Completed |
NCT05078320 -
Internet-delivered Cognitive-behaviour Therapy for Adolescents With Body Dysmorphic Disorder
|
N/A | |
| Recruiting |
NCT03918577 -
Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
|
N/A | |
| Completed |
NCT01398904 -
Attentional Bias in Body Dysmorphic Disorder
|
N/A | |
| Completed |
NCT03773549 -
A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder
|
||
| Recruiting |
NCT05607121 -
TMS Visual Modulation in Body Dysmorphic Disorder
|
N/A | |
| Completed |
NCT03221738 -
Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder
|
N/A | |
| Completed |
NCT04254575 -
Understanding Daily Changes in BDD Risk Using Smartphones
|
||
| Completed |
NCT04103606 -
A Mobile-App Training to Reduce Body Image Disorder Symptoms and Associated Features in Female University Students
|
N/A | |
| Recruiting |
NCT01093950 -
White Light Scanning to Aid Body Contouring: A Pilot Project
|
N/A | |
| Recruiting |
NCT04899687 -
Study of Dextromethorphan in OCD and Related Disorders
|
Phase 2 | |
| Completed |
NCT05612425 -
Text Message Safety Behavior Fading for Appearance Concerns
|
N/A | |
| Completed |
NCT06370559 -
Relationship Between Repetitive Negative Thinking and CBT Outcomes
|
||
| Recruiting |
NCT06262412 -
Internet-delivered Cognitive-behaviour Therapy for Child and Adolescent Body Dysmorphic Disorder
|
N/A | |
| Active, not recruiting |
NCT04034693 -
Waitlist-Control Trial of Smartphone CBT for Body Dysmorphic Disorder (BDD)
|
N/A | |
| Recruiting |
NCT06346301 -
Imagery Rescripting as a Stand-alone Treatment for OCD and BDD.
|
N/A | |
| Recruiting |
NCT01316627 -
Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions
|
Phase 2 | |
| Completed |
NCT03517384 -
Feasibility Pilot Study of Internet-based Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder With Global Recruitment
|
N/A |