Assessment of Body Composition and Physical Function

Body Composition Clinical Trial

— Perform  

Official title:

Assessment of Body Composition and Physical Function in Older Adults With Obesity

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05784571
• Other study ID #: PBRC 2023-001
• Status: Completed
• Start date: March 13, 2023
• Est. completion date: June 1, 2023

Study information

• Verified date: June 2023
• Source: Pennington Biomedical Research Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Sarcopenia, which is the loss of muscle mass and strength or physical function, naturally occurs in aging. In sarcopenic obesity, growth of muscle mass and increments in strength do not parallel weight gain, and places older adults at increased risk of falls, fractures, physical disability, frailty, and mortality from too low muscle strength relative to body size. The goal of the study is to assess body composition and physical function in older adults with obesity.

Description:

This is a cross-sectional study in 40 adults aged 60 to 80 years with obesity. Body composition, physical function, and insulin resistance will be measured. Subjects who satisfy the eligibility criteria and sign the informed consent will be enrolled. Subjects will complete an assessment of body composition by bioelectrical impedance analysis and tests of physical performance. Blood will be drawn for measurement of fasting glucose and insulin.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: June 1, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years to 80 Years

Eligibility

Inclusion Criteria:

• Body mass index > 30kg/m2

• Age 60 - 80 years

Exclusion Criteria:

• self-reported history of diabetes, or cancer or significant cardiovascular or hepatic or renal disease or dysfunction.

• clinically significant gastrointestinal malabsorption syndromes such as chronic diarrhea, or celiac disease.

Related Conditions & MeSH terms

• Body Composition
• Physical Function

Intervention

Other:
• Body Composition Assessment
Assessment of body composition using bioelectrical impedance analysis.
• Modified Physical Performance Test
A test of physical functioning
• Hand grip strength
A test of hand grip strength using a hand dynamometer.
• 6-minute walk test
Self-paced test of walking capacity.

Procedure:
• Measurement of blood glucose and insulin
Blood will be drawn for measurement of glucose and insulin.

Locations

Country	Name	City	State
United States	Pennington Biomedical Research Center	Baton Rouge	Louisiana

Sponsors (1)

Lead Sponsor	Collaborator
Pennington Biomedical Research Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fat mass	Measurement of fat mass	One day
Primary	Fat-free mass	Measurement of fat-free mass	One day
Primary	Modified Physical Performance Test	Assessment of physical function	One day
Secondary	Hand grip strength	Assessment of grip strength using a hand dynamometer	One day
Secondary	6-minute walk test	Test of walking capacity assessed as distance covered in 6 minutes	One day
Secondary	Insulin resistance	Assessment of insulin resistance from blood glucose and insulin	One day