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Rectal Misoprostol and Blood Loss During Abdominal Hysterectomy

Blood Loss Clinical Trial

Official title:
Evaluation of the Effect of Rectal Misoprostol on Blood Loss During Abdominal Hysterectomy: A Double Blind Randomized Controlled Trial.

Clinical Trial Summary

Hysterectomy, as any major operation, can cause complications, as hemorrhage which may occur in some cases and sometimes requiring blood transfusion. Recent study proved that misoprostol success in reducing blood loss during total abdominal hysterectomy when used once before the surgery.

Clinical Trial Description

In this study we tried to assess the efficacy of misoprostol in minimize blood loss during hysterectomy when used as single preoperative dose via rectal route. The reduction of blood flow may be due to the combined effect of myometrial contraction and vasoconstrictive effect ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02265562
Study type Interventional
Source Cairo University
Contact Waleed EL-khayat, M.D.
Phone 01005135542
Email waleed_elkhyat@yahoo.com
Status Recruiting
Phase Phase 3
Start date October 2014
Completion date June 2015
View Details
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