Effects of Blood Flow Restriction During Eccentric Resistance Exercise

Blood Flow Restriction Clinical Trial

Official title:

Effects of Blood Flow Restriction During Multiple-joint Eccentric Resistance Training on Muscle Morphology and Function of the Lower Body

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05606744
• Other study ID #: 12042a
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 1, 2023
• Est. completion date: March 1, 2024

Study information

• Verified date: November 2022
• Source: Utah State University
• Contact: Brennan J Thompson, PhD
• Phone: 435-797-5785
• Email: brennan.thompson[@]usu.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to compare the muscle strength and muscle soreness effects experienced following short term (acute) eccentric exercise with and without blood flow restriction (BFR) performed at low - moderate training intensities.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 45
• Est. completion date: March 1, 2024
• Est. primary completion date: December 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Exclusion Criteria:

• lower body surgery or injury in the last 12 months

• have any neuromuscular disease

• height >76 inches tall

• height <54 inches tall

• eccentric strength greater than 725 pounds

• pregnant or plan to be pregnant in the duration of the protocol

• don't do resistance exercise at least once per week

• perform intense cardio or strength training >4 days per week

• Present with any other significant comorbid conditions that would impair the ability to participate in the exercise-based testing

Inclusion criteria:

• 18 - 30 years old

• strength train lower body 1-3 times per week

Related Conditions & MeSH terms

• Blood Flow Restriction

Intervention

Device:
• Eccentric exercise / Eccentric exercise with blood flow restriction
Individuals will be randomized to receive eccentric exercise only, or eccentric exercise with blood flow restriction.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Utah State University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	visual analog scale (soreness)	soreness	Baseline (pretest)
Primary	visual analog scale (soreness)	soreness	immediately post exercise
Primary	visual analog scale (soreness)	soreness	24 hours post exercise
Primary	visual analog scale (soreness)	soreness	48 hours post exercise
Primary	visual analog scale (soreness)	soreness	72 hours post exercise
Primary	force algometer (soreness)	soreness	Baseline (pretest)
Primary	force algometer (soreness)	soreness	immediately post exercise
Primary	force algometer (soreness)	soreness	24 hours post exercise
Primary	force algometer (soreness)	soreness	48 hours post exercise
Primary	force algometer (soreness)	soreness	72 hours post exercise
Secondary	Eccentric muscle strength	muscle strength will be assessed on the Eccentron.	Baseline (pretest)
Secondary	Eccentric muscle strength	muscle strength will be assessed on the Eccentron.	immediately post exercise
Secondary	Eccentric muscle strength	muscle strength will be assessed on the Eccentron.	24 hours post exercise
Secondary	Eccentric muscle strength	muscle strength will be assessed on the Eccentron.	48 hours post exercise
Secondary	Eccentric muscle strength	muscle strength will be assessed on the Eccentron.	72 hours post exercise
Secondary	Single-leg hop	3 single-leg hops per limb	Baseline (pretest)
Secondary	Single-leg hop	3 single-leg hops per limb	immediately post exercise
Secondary	Single-leg hop	3 single-leg hops per limb	24 hours post exercise
Secondary	Single-leg hop	3 single-leg hops per limb	48 hours post exercise
Secondary	Single-leg hop	3 single-leg hops per limb	72 hours post exercise