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Blood Donors clinical trials

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NCT ID: NCT06021925 Recruiting - Blood Donors Clinical Trials

Obstetrical History and Anti-HLA Antibodies Level

OBS-HLA
Start date: December 13, 2023
Phase:
Study type: Observational

Chronic histiocytic intervillositis (CHI) is associated with severe and recurrent obstetrical complications. A link between anti-HLA Antibodies (Ab) and CHI has recently been established. At the Etablissement Français du Sang (EFS), donors who have already given birth once and have high levels of anti-HLA are excluded from donating apheresis platelets and therapeutic plasma to prevent TRALI (Transfusion Related Acute Lung Injury). No studies have examined the obstetrical history of these donors. The question is: is there an association between anti-HLA levels and obstetrical complications?

NCT ID: NCT04783077 Completed - Blood Donors Clinical Trials

Community-Based Communication Approaches for Blood Donation in Ghana

C-CAD
Start date: November 2, 2021
Phase: N/A
Study type: Interventional

DESIGN This pilot study utilizes a mixed-methods approach to develop a novel docu- drama communication strategy, design WhatsApp intervention, evaluate the feasibility of a larger pragmatic randomized controlled trial (RCT) of the two communication strategies and assess acceptability of the communication strategies aimed to increase blood donation among first-time blood donors within the catchment areas of the Southern Zonal Blood Centre (SZBC) in Ghana. In sequence, this pilot study and larger RCT are grounded in the PRECEDE-PROCEED implementation science framework. The pilot study has four components: 1) a qualitative component will be used to design a docu-drama, 2) key informant interviews to guide intervention development, 3) a simultaneous randomized pilot trial will evaluate the feasibility of the larger trial design of communication interventions using WhatsApp compared to control, and 4) a final mixed- methods (quantitative survey and focus groups) assessment of participant views of acceptability, effectiveness, feasibility and cultural appropriateness of the two proposed communication interventions. OBJECTIVES The three objectives of this pilot study are the careful design of a novel docu- drama communication intervention and WhatsApp intervention, evaluation of the feasibility of a larger RCT of communication strategies, and assessment of participant views of the two proposed communication interventions and control among first time blood donors within the catchment areas of the SZBC. For the purposes of registration for clinicaltrials.gov only the randomized pilot trial communication interventions using WhatsApp compared to control is reported. The planned sample size for the pilot RCT is n=128 first-time blood donors. The study population for the pilot RCT is first-time voluntary non-remunerated blood donors (VNRBD) and family/replacement blood donors (FRD) from the SZBC catchment area. REGIMEN WhatsApp: Participants assigned to the WhatsApp group will receive weekly messages developed by communication specialists aimed to motivate blood donation, be encouraged to discuss their blood donation experiences, and share their own motivations for donating blood in a moderated, closed group over a six-month duration. The moderator will provide guidelines on acceptable use of WhatsApp in the group, including images they can or cannot share. Participants will also receive standard NBSG communications for first-time donors. Control: Participants in this group will receive the standard NBSG communications for first-time donors: 1) a thank you phone call and 2) and a reminder phone call two-weeks prior to the second blood donation eligibility. The second blood donation eligibility is four months after the first donation.

NCT ID: NCT04088695 Completed - Blood Donors Clinical Trials

Effect of a Web Page Based on a Motivational Video for Voluntary Blood Donation

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Voluntary blood donation is currently a key issue in many countries, as the shortage of voluntary donors results in a deficit in the supplies of the Blood Banks of the hospitals. One factor for which there is a low number of voluntary donors is the limited dissemination of information that is given to the population regarding the facilities and benefits of blood donation. Objective: To evaluate the effect of a web page containing a motivational video and an informative text to promote the voluntary donation of blood disseminated through the use of social networks such as Facebook and WhatsApp. Design and Participants: Online randomized controlled trial for a group of 102 university students. Intervention: One group exposed to the intervention with video and the other control group exposed to informative text.

NCT ID: NCT04078893 Recruiting - Blood Donors Clinical Trials

The Effect of Recruiting Inactive Blood Donors Using Different Means

Start date: October 20, 2019
Phase: N/A
Study type: Interventional

14098 inactive donors were randomly divided into three groups according to age, sex, blood donation frequency,time of last donation and blood donation site, one group acted as the control group, one will be recruited by telephone recruitment on "need", and one will just be called for improvement suggestions of blood donor service.

NCT ID: NCT03988738 Completed - Blood Donors Clinical Trials

Promoting Repeat Blood Donation Through Social Media Among First-time Donors in a Peruvian Blood Bank

Start date: June 20, 2019
Phase: N/A
Study type: Interventional

Blood donations are an important need worldwide. In Peru, only 10% of donations are voluntary, of which only a quarter are repeat donors. Repeat donations are crucial to maintaining a safe and adequate blood supply. Social media presents a unique opportunity to promote blood donation, because of its increasing use and its prior successes in promoting positive health-related behaviors . The present study aims to develop and evaluate a social media intervention - Facebook and WhatsApp - to improve communication and promote repeat blood donations in voluntary first-time donors attending donation campaigns organized by the Hospital Nacional Cayetano Heredia (HCH).

NCT ID: NCT03835299 Completed - Blood Donors Clinical Trials

Addressing Fear and Risk of Vasovagal Reactions Among High School Donors

Start date: February 15, 2019
Phase: N/A
Study type: Interventional

In this study, high school donors will be asked about their blood donation-related fears prior to their donation. Half of the donors reporting fear will be assigned to a brief coping skills intervention.

NCT ID: NCT03102385 Completed - Blood Donors Clinical Trials

A Survey of Attitudes of Experienced Blood Donors

Start date: April 3, 2017
Phase: N/A
Study type: Interventional

This study examines the effects of a web-based motivational interview on 1) internal motivation to donate blood; 2) donor autonomy, competence and relatedness; and 3) donation intention and behavior. The study also evaluates whether group differences in donation intention and behavior are mediated by autonomy, competence, and relatedness, and in turn, internal motivation.

NCT ID: NCT02717338 Completed - Blood Donors Clinical Trials

Blood Donor Competence, Autonomy and Relatedness Enhancement

Start date: May 27, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether enhancing blood donor competence, autonomy, and/or relatedness increases intrinsic motivation to donate and improves donor retention.

NCT ID: NCT02274064 Completed - Blood Donors Clinical Trials

Motivating Type O- Blood Donors to Return

Start date: November 2014
Phase: N/A
Study type: Interventional

This study develops a motivational interview and implementation intention intervention for blood donor retention and tests the efficacy of this new approach among first-time, Group O donors.

NCT ID: NCT02145507 Completed - Blood Donors Clinical Trials

Evaluation of Whole Blood With CPD Anticoagulant and AS-7/SOLX Additive Solution

Start date: April 2014
Phase: Phase 1
Study type: Interventional

This study will evaluate a new blood collection and filtration system that is intended to be used to collect, filter, separate and store red blood cells and, separately, plasma. The new blood collection and filtration system will be compared to an already-approved and currently used system. Further, this study will evaluate new processing conditions relative to the individual components of the collection and filtration system. All study participants will donate two units of whole blood with individual units being donated at least 56 days apart. One unit of whole blood will be donated with the new system, and the other unit will be collected with the already-approved system. A subset of the donors (approximately 24 of the 120 participants) will have a small quantity of their red blood cells injected back into their body 42-days after they were donated in order to evaluate how well the red blood cells survive. Blood and blood products from all donors will be analyzed the day of collection and after storage (plasma after at least 30 days of storage and red blood cells after exactly 42 days of storage).