Sugammadex Reversal of Neuromuscular Blockade and Postoperative Bleeding

Blood Coagulation Tests ( INR, APTT) Clinical Trial

— Suga_bleeding  

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02939430
• Other study ID #: Refa-suga-bleeding
• Status: Recruiting
• Phase: N/A
• First received: October 17, 2016
• Last updated: February 5, 2017
• Start date: November 2016
• Est. completion date: November 2017

Study information

• Verified date: February 2017
• Source: Mansoura University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Sugammadex is new drug that is used for reversal of rocuronium induced muscle relaxation. benefits of reversal of neuromuscular blockade appears to be of great value in living donor liver transplant recipients. However, Few Clinical reports have investigated the anticoagulant effect of sugammadex. In this study, effects of sugammadex on bleeding profile of living donor liver transplantation will be investigated.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: November 2017
• Est. primary completion date: October 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• all candidates for living donor liver transplantation

Exclusion Criteria:

• massive intraoperative bleeding manifestations of early graft dysfunction

Related Conditions & MeSH terms

• Blood Coagulation Tests ( INR, APTT)

Intervention

Drug:
• Sugammadex intravenous
Intravenous Injection of sugammadex (2 mg/kg) for reversal of rocuronium induced muscle relaxation
• Intravenous neostigmine and atropine

Locations

Country	Name	City	State
Egypt	Gastroenterology center	Mansoura
Egypt	Mansoura university	Mansoura	Dkahleya

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	activated partial thromboplastin tile in seconds		30 min
Secondary	international normalized ratio in second		30 min